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Erythema Nodosum Masking Kawasaki Disease with an Initial Manifestation of Skin Lesions

机译:红斑结节掩盖了川崎病并初步表现出皮肤病变

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摘要

We report the first case demonstrating an association between Kawasaki disease (KD) and erythema nodosum (EN). A 3-year-old girl presented with EN as an initial manifestation of KD. At the initial visit, she showed high fever of 40℃, injection of the oropharynx, cervical lymphadenopathy, and red-purple cutaneous nodules, particularly on the lower limbs. She complained of severe pain in the neck and cutaneous lesions. Initially, the development of EN was attributed to Salmonella spp infection, which was detected in stool culture. However, the patient did not respond to high-dose ampicillin/sulbactam to which the Salmonella spp is sensitive. Echocardiography performed as screening for fever of unknown origin revealed medium-sized aneurysms of the left anterior descending artery. EN masked the diagnosis of KD, and the patient developed a coronary artery lesion. KD should be considered in the differential diagnosis of refractory EN in pediatric patients.
机译:我们报告的第一例表明川崎病(KD)和结节性红斑(EN)之间存在关联。一名3岁女孩因EN表现为KD的最初表现。初次访视时,她表现出40℃的高烧,口咽注射,宫颈淋巴结病和红紫色的皮肤结节,尤其是在下肢。她抱怨颈部和皮肤病变严重疼痛。最初,EN的发展归因于沙门氏菌感染,在粪便培养中被发现。但是,患者对沙门氏菌属敏感的大剂量氨苄西林/舒巴坦无反应。超声心动图检查不明原因的发热,发现左前降支动脉有中等大小的动脉瘤。 EN掩盖了KD的诊断,患者发展为冠状动脉病变。儿科患者难治性EN的鉴别诊断中应考虑KD。

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