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Data on molecular characterization and gene expression analysis of secretory carrier-associated membrane protein 5 (SCAMP5) from the red sea bream (Pagrus major)

机译:红鲷(Pagrus major)分泌性载体相关膜蛋白5(SCAMP5)的分子表征和基因表达分析数据

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摘要

Secretory carrier membrane proteins (SCAMPs) are widely distributed integral membrane proteins implicated in membrane trafficking. Secretory carrier membrane protein 5 (SCAMP5) is expected to be involved in regulation of the immune response because it is expressed in a variety of immune tissues and promotes the secretion of cytokines in monocytes and macrophages. In this study, we performed an analysis of the molecular characteristics and phylogenetic of the SCAMP5 gene identified in Pagrus major (PmSCAMP5). In addition, we analysed PmSCAMP5 gene expression levels in the tissues of red sea bream infected with various pathogens [Edwardsiella piscicida (E. piscicida), Streptococcus iniae (S. iniae) and Red sea bream iridovirus (RSIV)], and we analysed PmSCAMP5 gene expression levels in the tissues of healthy red sea bream. This study was carried out to provide basic data on the non-specific immune system of the red sea bream.
机译:分泌性载体膜蛋白(SCAMP)是涉及膜运输的广泛分布的整合膜蛋白。分泌型载体膜蛋白5(SCAMP5)有望参与免疫应答的调节,因为它在多种免疫组织中表达并促进单核细胞和巨噬细胞中细胞因子的分泌。在这项研究中,我们进行了对在主要Pagrus(PmSCAMP5)中识别的SCAMP5基因的分子特征和系统发育的分析。此外,我们分析了感染各种病原体的红鲷鱼组织中的PmSCAMP5基因表达水平[Edwardsiella piscicida(E. piscicida),链球菌(S. iniae)和红鲷鱼虹膜病毒(RSIV)],并分析了PmSCAMP5健康红鲷鱼组织中的基因表达水平。进行这项研究以提供关于红鲷的非特异性免疫系统的基础数据。

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