Single Nucleotide Polymorphisms in BCO1 and CD36 Are Related to Macular Pigment Among Children (OR05-04-19)

机译：BCO1和CD36中的单核苷酸多态性与儿童黄斑色素有关（OR05-04-19）

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ObjectivesXanthophyll carotenoids in the retina have been linked to visual and cognitive health. While genetic variations in genes related to carotenoid cleavage (e.g., beta-carotene-15,15′-monooxygenase [BCO1/BCMO1]) and xanthophyll transport (e.g., Cluster Determinant 36 [CD36]) proteins have been shown to influence MPOD in adults, it is unknown whether these relationships are evident in childhood. We examined the influence of genetic variation (single nucleotide polymorphisms [SNPs]) in BCO1 and CD36 on MPOD in 7–10 year-olds (N = 134).

机译：目的视网膜中的叶黄素类胡萝卜素与视觉和认知健康有关。虽然已显示与类胡萝卜素切割相关的基因（例如，β-胡萝卜素-15,15'-单加氧酶[BCO1 / BCMO1]）和叶黄素转运（例如，簇决定簇36 [CD36]）的基因变异会影响成年人的MPOD尚不清楚这些关系在儿童时期是否很明显。我们检查了7-10岁（N = 134）BCO1和CD36的遗传变异（单核苷酸多态性[SNPs]）对MPOD的影响。

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期刊名称 Current Developments in Nutrition
作者
Ruyu Liu; Bridget Hannon; Katie Robinson; Lauren Raine; Billy Hammond; Lisa Renzi-Hammond; Neal Cohen; Arthur Kramer; Charles Hillman; Margarita Teran-Garcia; Naiman Khan;
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年(卷),期 2019(3),Suppl 1
年度 2019
页码 OR05-04-19
总页数 1
原文格式 PDF
正文语种
中图分类营养学;
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专利

1. Single-Nucleotide Polymorphisms Associated With Age-Related Macular Degeneration and Lesion Phenotypes in the Comparison of Age-Related Macular Degeneration Treatments Trials [J] . Maguire Maureen G., Ying Gui-shuang, Jaffe Glenn J., JAMA ophthalmology . 2016,第6期

机译：单核苷多态性与年龄相关性黄斑变性和病变表型相关的年龄相关性黄斑变性治疗试验的比较。
2. Evaluation of the relationship between MARCO and CD36 single-nucleotide polymorphisms and susceptibility to pulmonary tuberculosis in a Chinese Han population [J] . Wenting Lao, Hui Kang, Guojiang Jin, BMC Infectious Diseases . 2017,第1期

机译：中国汉族人群肺结核与肺结核多态性与肺结核的关系的评价
3. Evaluation of the relationship between CD36 and MARCO single-nucleotide polymorphisms and susceptibility to carotid atherosclerosis in a Chinese Han population [J] . Yang Chu, Wenting Lao, Guojiang Jin, Gene: An International Journal Focusing on Gene Cloning and Gene Structure and Function . 2017,第期

机译：CD36和Marco单核苷酸多态性与中国汉族人群中颈动脉粥样硬化的关系的评价
4. Single Nucleotide Polymorphisms of CD14 Are Associated with the Development of Respiratory Syncytial Virus Bronchiolitis in Japanese Children [C] . Y. Inoue, N. Shimojo, E.J. Campos, Collegium Internationale Allergologicum . 2007

机译：CD14的单核苷酸多态性与日本儿童呼吸道合胞病毒支气管炎的发育有关
5. Investigating determinants of macular pigment optical density and macular pigment distribution in adults aged 45--73: Can enhanced analytical techniques improve the ability to predict macular pigment status? [D] . Burke, Joanne Delaney. 2001

机译：调查45--73岁成年人黄斑色素光密度和黄斑色素分布的决定因素：增强的分析技术能否提高预测黄斑色素状态的能力？
6. Single-Nucleotide Polymorphisms Associated With Age-Related Macular Degeneration and Lesion Phenotypes in the Comparison of Age-Related Macular Degeneration Treatments Trials [O] . Maureen G. Maguire, Gui-shuang Ying, Glenn J. Jaffe, -1

机译：单核糖多态性与年龄相关性黄斑变性和病变表型相关的年龄相关性黄斑变性治疗试验的比较。
7. Single-Nucleotide Polymorphisms Associated With Age-Related Macular Degeneration and Lesion Phenotypes in the Comparison of Age-Related Macular Degeneration Treatments Trials [O] . Maureen G. Maguire, Gui-shuang Ying, Glenn J. Jaffe, 2016

机译：与年龄相关的黄斑变性和病变表型相关的单核苷酸多态性在与年龄相关的黄斑治疗试验的比较中

Single Nucleotide Polymorphisms in BCO1 and CD36 Are Related to Macular Pigment Among Children (OR05-04-19)

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