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Clinical review: Canadian National Advisory Committee on Blood and Blood Products - Massive Transfusion Consensus Conference 2011: report of the panel

机译:临床评价:加拿大全国血液和血液制品咨询委员会-2011年大规模输血共识会议:小组报告

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摘要

In June 2011 the Canadian National Advisory Committee on Blood and Blood Products sponsored an international consensus conference on transfusion and trauma. A panel of 10 experts and two external advisors reviewed the current medical literature and information presented at the conference by invited international speakers and attendees. The Consensus Panel addressed six specific questions on the topic of blood transfusion in trauma. The questions focused on: ratio-based blood resuscitation in trauma patients; the impact of survivorship bias in current research conclusions; the value of nonplasma coagulation products; the role of protocols for delivery of urgent transfusion; the merits of traditional laboratory monitoring compared with measures of clot viscoelasticity; and opportunities for future research. Key findings include a lack of evidence to support the use of 1:1:1 blood component ratios as the standard of care, the importance of early use of tranexamic acid, the expected value of an organized response plan, and the recommendation for an integrated approach that includes antifibrinolytics, rapid release of red blood cells, and a foundation ratio of blood components adjusted by results from either traditional coagulation tests or clot viscoelasticity or both. The present report is intended to provide guidance to practitioners, hospitals, and policy-makers.
机译:2011年6月,加拿大全国血液和血液制品咨询委员会主办了一次有关输血和创伤的国际共识会议。由10位专家和2位外部顾问组成的小组审议了国际会议邀请的国际演讲者和与会人员介绍的最新医学文献和信息。共识小组讨论了关于创伤输血的六个具体问题。问题集中在:创伤患者中基于比例的血液复苏;生存偏差对当前研究结论的影响;非血浆凝血产品的价值;协议在紧急输血中的作用;与凝块粘弹性测量相比,传统实验室监测的优点;和未来研究的机会。主要发现包括缺乏证据支持使用1:1:1的血液成分比率作为护理标准,早期使用氨甲环酸的重要性,有组织的应对计划的预期价值以及综合建议包括抗纤溶剂,红细胞快速释放以及通过传统凝血试验或凝块粘弹性或两者的结果调整的血液成分的基础比率的方法。本报告旨在为从业人员,医院和政策制定者提供指导。

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