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Microbial Consortia Engineering for Cellular Factories: in vitro to in silico systems

机译:细胞工厂的微生物联盟工程:体外到计算机系统

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摘要

This mini-review discusses the current state of experimental and computational microbial consortia engineering with a focus on cellular factories. A discussion of promising ecological theories central to community resource usage is presented to facilitate interpretation of consortial designs. Recent case studies exemplifying different resource usage motifs and consortial assembly templates are presented. The review also highlights in silico approaches to design and to analyze consortia with an emphasis on stoichiometric modeling methods. The discipline of microbial consortia engineering possesses a widely accepted potential to generate highly novel and effective bio-catalysts for applications from biofuels to specialty chemicals to enhanced mineral recovery.
机译:这份小型回顾讨论了实验和计算微生物联盟工程的当前状态,重点是细胞工厂。提出了对社区资源利用至关重要的有前途的生态学理论的讨论,以促进对财团设计的解释。最近的案例研究举例说明了不同的资源使用主题和联合体组装模板。该评论还重点介绍了计算机设计和分析财团的计算机方法,重点是化学计量建模方法。微生物联合体工程学科具有广泛的潜力,可以产生高度新颖和有效的生物催化剂,用于从生物燃料到特种化学品的应用,以提高矿物质的回收率。

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