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Recent update of the 2017 Korean Association for the Study of the Liver (KASL) treatment guidelines of chronic hepatitis C: Comparison of guidelines from other continents 2017 AASLD/IDSA and 2016 EASL

机译:2017年韩国慢性肝炎肝病研究协会(KASL)治疗指南的最新更新:其他大洲2017年AASLD / IDSA和2016年EASL指南的比较

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摘要

The paradigm for the treatment of chronic hepatitis C (CHC) has been changed due to the development of direct acting antivirals (DAAs) of hepatitis C virus (HCV). The high sustained virologic response rate and ease of administration makes the DAAs approach ideal to contribute to the complete eradication of HCV. Currently, treatment options for individual patients vary depending on the genotype or subtype of HCV, presence or absence of liver cirrhosis, previous experience of antiviral treatment or resistance associated substitutions. Because of drug avalilability, cost-effectiveness, preference, compliance and greater possibility of desirable effects and presumed patient-important outcomes may vary between countries, treatment options for individual patients are different. The review focuses on the comparing the current treatment options for CHC in other continents with the 2017 Korea Association for the Study of the Liver guidelines.
机译:由于丙型肝炎病毒(HCV)的直接作用抗病毒药(DAA)的开发,已改变了治疗慢性丙型肝炎(CHC)的范例。高持续病毒学应答率和易于管理使DAA方法成为完全根除HCV的理想选择。当前,针对个体患者的治疗选择取决于HCV的基因型或亚型,是否存在肝硬化,先前的抗病毒治疗经验或耐药性相关替代。由于药物的可获得性,成本效益,偏好,依从性以及更大的可能的预期效果以及患者对患者的重要结局可能因国家而异,因此针对单个患者的治疗选择也有所不同。审查的重点是将其他大洲当前的CHC治疗方案与2017年韩国肝病研究协会指南进行比较。

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