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Barrett Esophagus: When to Endoscope

机译:巴雷特食管:什么时候去内窥镜

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摘要

Increasing interest in identifying an effective strategy for decreasing the burden of esophageal adenocarcinoma (EAC) has been fuelled by the rising EAC rates worldwide, the morbidity associated with esophagectomy, and the development of endoscopic methods for curing early-stage EAC. In the face of this enthusiasm, however, we should be cautious about continuing our current evidence-free approach to screening and one with unclear benefits and unclear costs to the community. The literature is increasingly recognizing that the value of traditional endoscopy for screening and surveillance of Barrett esophagus may be more limited than initially believed. A better understanding of the risk factors for Barrett esophagus and progression to dysplasia and a more individualized risk calculation will be useful in defining populations to consider for Barrett screening. The development of novel, nonendoscopic screening techniques and of less expensive endoscopic techniques holds promise for a cost-effective screening and surveillance method to curtail the increasing rates of EAC.
机译:全球范围内EAC比率不断上升,与食管切除术相关的发病率以及内镜治疗早期EAC的方法的发展,促使人们越来越有兴趣寻找减轻食管腺癌(EAC)负担的有效策略。但是,面对这种热情,我们应谨慎对待继续采用当前无证据的筛查方法,并且该方法对社区的好处和成本都不明确。越来越多的文献认识到,传统的内窥镜检查对Barrett食管的筛查和监测的价值可能比最初认为的更为有限。更好地了解Barrett食道和发展为不典型增生的危险因素,以及更加个性化的风险计算,对于定义要考虑进行Barrett筛查的人群将很有用。新型,非内窥镜检查技术和较便宜的内窥镜检查技术的发展,有望成为一种经济有效的筛查和监视方法,以减少EAC的发病率。

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