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Histone deacetylation of memory T lymphocytes by You-Gui-Wan alleviates allergen-induced eosinophilic airway inflammation in asthma

机译：尤桂皖组蛋白对记忆T淋巴细胞的去乙酰化作用减轻哮喘中变应原诱导的嗜酸性气道炎症

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BackgroundYou-Gui pills (You-Gui-Wan; YGW) can promote T lymphocyte proliferation and differentiation, and restore Th1/Th2 balance in the treatment of asthma, but their mechanism of action is not fully known. This study aims to explore whether YGW can induce histone deacetylation or acetylation in memory T lymphocytes (Tm) for improvement of airway inflammation in asthma.

机译：背景优桂丸（You-Gui-Wan； YGW）可以促进T淋巴细胞的增殖和分化，并在哮喘的治疗中恢复Th1 / Th2的平衡，但其作用机理尚不清楚。这项研究旨在探讨YGW是否可以在记忆T淋巴细胞（Tm）中诱导组蛋白脱乙酰化或乙酰化，从而改善哮喘的气道炎症。

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期刊名称 Chinese Medicine
作者
Hong Ping Zhang; Juan Juan Fu; Tao Fan; Wen Bin Zhang; Zeng Li Wang; Lei Wang; Gang Wang;
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作者单位

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年(卷),期 2015(10),-1
年度 2015
页码 9
总页数 11
原文格式 PDF
正文语种
中图分类药学;
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专利

1. Histone deacetylation of memory T lymphocytes by You-Gui-Wan alleviates allergen-induced eosinophilic airway inflammation in asthma [J] . Hong P Zhang, Juan J Fu, Tao Fan, Chinese Medicine . 2015,第1期

机译：尤桂皖组蛋白对记忆T淋巴细胞的去乙酰化作用减轻哮喘中变应原诱导的嗜酸性气道炎症
2. Association between histone hyperacetylation status in memory T lymphocytes and allergen-induced eosinophilic airway inflammation [J] . Zhang Hong Ping, Wang Lei, Fu Juan Juan, Respirology : . 2016,第5期

机译：记忆T淋巴细胞组蛋白超乙酰化状态与变应原诱导的嗜酸性气道炎症之间的关系
3. Potential contribution of IL-7 to allergen-induced eosinophilic airway inflammation in asthma. [J] . Kelly EA, Koziol-White CJ, Clay KJ, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2009,第3期

机译：IL-7对过敏原诱导的哮喘嗜酸性气道炎症的潜在作用。
4. Enhancement of Antigen-Induced Eosinophilic Inflammation in the Airways of Mice by Urban Particles in Beijing [C] . Miao He, Takamichi Ichinose, Seiichi Yoshida, Conference on Environmental Pollution and Public Health . 2012

机译：北京城市颗粒增强抗原诱导的小鼠气道嗜酸性粒细胞炎症
5. Innate immunity in allergen-induced airway inflammation Role of macrophage migration inhibitory factor (MIF) and cholesterol 25-hydroxylase (CH25H) in alveolar macrophages. [D] . Park, Kiwon. 2011

机译：过敏原诱导的气道炎症中的先天免疫肺泡巨噬细胞中巨噬细胞迁移抑制因子（MIF）和胆固醇25-羟化酶（CH25H）的作用。
6. Potential Contribution of IL-7 to Allergen-Induced Eosinophilic Airway Inflammation in Asthma [O] . Elizabeth A. B. Kelly, Cynthia Koziol, Kathryn J. Clay, -1

机译：IL-7对哮喘致敏原诱导的嗜酸性气道炎症的潜在贡献
7. Histone deacetylation of memory T lymphocytes by alleviates allergen-induced eosinophilic airway inflammation in asthma [O] . 2015

机译：缓解哮喘中变应原诱导的嗜酸性气道炎症的组蛋白使记忆T淋巴细胞脱乙酰化

Histone deacetylation of memory T lymphocytes by You-Gui-Wan alleviates allergen-induced eosinophilic airway inflammation in asthma

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