首页> 美国卫生研究院文献>Case Reports in Orthopedics >Treatment of Knee Osteochondral Lesions Using a Novel Clot of Autologous Plasma Rich in Growth Factors Mixed with Healthy Hyaline Cartilage Chips and Intra-Articular Injection of PRGF
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Treatment of Knee Osteochondral Lesions Using a Novel Clot of Autologous Plasma Rich in Growth Factors Mixed with Healthy Hyaline Cartilage Chips and Intra-Articular Injection of PRGF

机译:使用富含生长因子的自体血浆与健康的透明软骨芯片混合并关节内注射PRGF来治疗膝骨软骨病

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摘要

Knee cartilage or osteochondral lesions are common and challenging injuries. To date, most symptomatic lesions warrant surgical treatment. We present two cases of patients with knee osteochondral defects treated with a one-step surgical procedure consisting of an autologous-based matrix composed of healthy hyaline cartilage chips, mixed plasma poor-rich in platelets clot, and plasma rich in growth factors (PRGF). Both patients returned to playing soccer at the preinjury activity level and demonstrated excellent defect filling in both magnetic resonance imaging and second-look arthroscopy (in one of them). The use of a clot of autologous plasma poor in platelets with healthy hyaline cartilage chips and intra-articular injection of plasma rich in platelets is an effective, easy, and cheap option to treat knee cartilage injuries in young and athletic patients.
机译:膝关节软骨或骨软骨损伤是常见且具有挑战性的伤害。迄今为止,大多数症状性病变需要手术治疗。我们介绍了两例膝关节骨软骨缺损患者,这些患者均接受了一步手术治疗,该手术包括基于自体的基质,该基质包括健康的透明软骨芯片,贫血的血小板混合血浆和富含生长因子的血浆(PRGF) 。两名患者均以损伤前的活动水平重新踢足球,并在磁共振成像和二次透视关节镜检查(其中之一)中表现出出色的缺损填补率。在健康的透明软骨碎片的血小板中使用自体血浆凝块,并在关节内注射富含血小板的血浆,是治疗年轻和运动患者膝关节软骨损伤的有效,简便且廉价的选择。

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