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Short-term outcomes after hospital discharge in patients admitted with heart failure in Abeokuta Nigeria: Data from the Abeokuta Heart Failure Registry

机译:尼日利亚阿贝库塔心力衰竭住院患者出院后的短期结局:阿贝库塔心力衰竭登记处的数据

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摘要

Heart failure (HF) has emerged as a global epidemic in at-risk populations, including those living in high-income countries and, as recently described, in low- to middle-income regions of the world, such as sub-Saharan Africa.1- While there are well-established HF registries to capture both the characteristics and health outcomes among those hospitalised with AHF in Europe,, North America,, and the Asia–Pacific region,,, there are few reports from sub-Saharan Africa. This includes Nigeria (the most populous country in the region), where HF has emerged as a potentially large public health problem.Although there have been many therapeutic gains in the management of chronic HF, leading to improved overall survival rates, there has been very little parallel success (pending further evaluation of the recently reported RELAX trial with regard to AHF). This is particularly important when one considers the high proportion of patients who still require hospitalisation for acute HF, and associated high levels of in-patient case fatality and poor short- to medium-term health outcomes.Given the paucity of data describing health outcomes in unselected patients hospitalised with AHF in Nigeria (and indeed the wider sub-Saharan Africa), we examined short- (30 days) to medium-term outcomes (180 days) in consecutive subjects with AHF recruited into the Abeokuta HF registry over a period of six months. Standardised data collected via the registry were used to both describe the baseline characteristics of the cohort and identify correlates of mortality during the six-month follow up.
机译:心力衰竭(HF)已成为高危人群的全球流行病,包括生活在高收入国家以及最近在世界低收入至中等收入地区(例如撒哈拉以南非洲)的人群。 1-尽管在欧洲,北美和亚太地区已有建立完善的HF注册机构来记录AHF住院患者的特征和健康结局,但撒哈拉以南非洲的报道却很少。其中包括尼日利亚(该地区人口最多的国家),HF已成为潜在的大范围公共卫生问题。尽管在慢性HF的管理方面取得了许多治疗方面的进展,从而提高了总体生存率,但几乎没有并行成功的结果(有待对最近报道的有关AHF的RELAX试验进行进一步评估)。当考虑到仍然需要因急性心力衰竭住院的患者比例很高,并伴有较高的住院病死率和较差的中短期健康结果时,这一点尤其重要。在尼日利亚(乃至更广泛的撒哈拉以南非洲地区)住院但未选择过AHF的患者,我们在连续30个月内将AHF纳入Abeokuta HF登记表的连续受试者中,检查了短期(30天)至中期结果(180天)六个月。通过注册表收集的标准化数据既用于描述队列的基线特征,也用于确定六个月随访期间的死亡率相关性。

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