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Appropriateness of Adrenocorticotropic Hormone Stimulation Test for Critically Ill Patients

机译:危重病人的促肾上腺皮质激素刺激试验的适当性

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摘要

Background:In earlier work, it was shown that patients with septic shock who also have adrenal insufficiency experience a benefit in terms of lower mortality rates with hydrocortisone supplementation. As such, the adrenocorticotropic hormone (ACTH) stimulation test has been used frequently to identify these patients. However, recent evidence has suggested that the identification and treatment of adrenal insufficiency in patients with septic shock does not reduce mortality. These results call into question the utility of the ACTH stimulation test in this patient population.
机译:背景:在较早的工作中,已证实败血症性休克患者也有肾上腺功能不全,可通过补充氢化可的松降低死亡率,从而受益。因此,促肾上腺皮质激素(ACTH)刺激测试已被频繁用于识别这些患者。但是,最近的证据表明,败血性休克患者的肾上腺功能不全的识别和治疗并不能降低死亡率。这些结果令人质疑ACTH刺激测试在该患者人群中的效用。

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