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Agricultural pesticide exposure and perinatal mortality in central Sudan.

机译:苏丹中部的农业农药暴露和围产期死亡率。

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摘要

Hospital- and community-based studies were conducted in central Sudan to investigate the association between pesticide exposure and perinatal mortality. The cases were 197 stillbirths in the hospital and 36 perinatal deaths in the community; the controls were 812 liveborn, normal-birth-weight infants in the hospital, and 1505 liveborn infants who survived for the first 7 days after birth in the community. The odds ratio (OR) of perinatal death associated with pesticide exposure was estimated using multiple logistic regression. There was a consistent and significant association between pesticide exposure and perinatal mortality in the hospital (adjusted OR = 1.9; 95% confidence interval (CI): 1.3-2.8) and the community populations (adjusted OR = 2.7; 95% CI: 1.1-6.4). The OR was significantly higher among women engaged in farming (3.6; 95% CI: 1.6-8.0), but not among women in nonfarming occupations (1.6; 95% CI: 0.8-3.3). The estimated attributable risks of perinatal death owing to pesticide exposure were 22.6% for hospital stillbirths and 15.7% for community perinatal deaths; but among women engaged in farming in the hospital population the attributable risks were substantially higher (34.5%).
机译:在苏丹中部进行了基于医院和社区的研究,以调查农药暴露与围产期死亡率之间的关系。病例为医院死产197例,社区死亡36例。对照组为812例在医院出生的体重正常出生的婴儿,以及1505例在社区出生后头7天存活的存活婴儿。使用多重逻辑回归估计与农药暴露相关的围产期死亡的比值比(OR)。在医院(调整后的OR = 1.9; 95%置信区间(CI):1.3-2.8)和社区人群(调整后的OR = 2.7; 95%CI:1.1-)之间,农药暴露与围产期死亡率之间存在一致且显着的关联。 6.4)。从事耕作的妇女的OR显着较高(3.6; 95%CI:1.6-8.0),但从事非农业职业的妇女则没有(1.6; 95%CI:0.8-3.3)。估计由于农药接触造成的围产期死亡风险为:医院死产为22.6%,社区围产期死亡为15.7%;但在医院人口中从事农业工作的妇女中,可归因的风险要高得多(34.5%)。

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