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Validation of the prognostic gene portfolio ClinicoMolecular Triad Classification using an independent prospective breast cancer cohort and external patient populations

机译：使用独立的前瞻性乳腺癌队列和外部患者人群验证预后基因组合ClinicoMolecular Triad分类

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IntroductionUsing genome-wide expression profiles of a prospective training cohort of breast cancer patients, ClinicoMolecular Triad Classification (CMTC) was recently developed to classify breast cancers into three clinically relevant groups to aid treatment decisions. CMTC was found to be both prognostic and predictive in a large external breast cancer cohort in that study. This study serves to validate the reproducibility of CMTC and its prognostic value using independent patient cohorts.

机译：引言最近，使用前瞻性乳腺癌患者队列的全基因组表达谱，临床分子三分类法（CMTC）得以开发，将乳腺癌分为三个临床相关组以帮助治疗决策。在该研究中，在大型外部乳腺癌队列中发现CMTC具有预后性和预测性。这项研究旨在使用独立的患者队列来验证CMTC的可重复性及其预后价值。

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期刊名称 Breast Cancer Research : BCR
作者
Dong-Yu Wang; Susan J Done; David R Mc Cready; Wey L Leong;
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作者单位

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年(卷),期 2014(16),4
年度 2014
页码 R71
总页数 11
原文格式 PDF
正文语种
中图分类肿瘤学;
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专利

1. Validation of the prognostic gene portfolio, ClinicoMolecular Triad Classification, using an independent prospective breast cancer cohort and external patient populations [J] . Dong-Yu Wang, Susan J Done, David R Mc Cready, Breast Cancer Research . 2014,第4期

机译：使用独立的前瞻性乳腺癌队列和外部患者人群验证预后基因组合，ClinicoMolecular Triad分类
2. Comprehensive geriatric assessment in older patients with cancer: an external validation of the multidimensional prognostic index in a French prospective cohort study [J] . Evelyne Liuu, Chunyun Hu, Simon Valero, BMC Geriatrics . 2020,第1期

机译：老年癌症患者的综合性老年评估：法国预期队列研究中多维预后指数的外在验证
3. Prospective multicenter validation of the independent prognostic value of the mitotic activity index in lymph node-negative breast cancer patients younger than 55 years. [J] . Baak JP, van Diest PJ, Voorhorst FJ, Journal of Clinical Oncology . 2005,第25期

机译：在55岁以下的淋巴结阴性乳腺癌患者中，有丝分裂活动指数的独立预后价值的前瞻性多中心验证。
4. Validation of a Quantifier-Based Fuzzy Classification System for Breast Cancer Patients on External Independent Cohorts [C] . Daniele Soria, Jonathan M. Garibaldi IEEE International Conference on Machine Learning and Applications . 2016

机译：基于量词的乳腺癌患者外部独立队列模糊分类系统的验证
5. Breast cancer risk and environmental factors—tobacco smoke and cooking fumes: A prospective cohort study of Shanghai women [D] . Zhu, Honghong 2007

机译：乳腺癌风险和环境因素—吸烟和吸烟：上海女性的前瞻性队列研究
6. Comprehensive geriatric assessment in older patients with cancer: an external validation of the multidimensional prognostic index in a French prospective cohort study [O] . Evelyne Liuu, Chunyun Hu, Simon Valero, 2020

机译：老年癌症患者的综合性老年评估：法国预期队列研究中多维预后指数的外在验证
7. Validation of the prognostic gene portfolio, ClinicoMolecular Triad Classification, using an independent prospective breast cancer cohort and external patient populations [O] . Dong-Yu Wang, Susan J Done, David R Mc Cready, 2014

机译：使用独立的前瞻性乳腺癌队列和外部患者人群验证预后基因组合，ClinicoMolecular Triad分类

Validation of the prognostic gene portfolio ClinicoMolecular Triad Classification using an independent prospective breast cancer cohort and external patient populations

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