Intake of St Johns wort improves the glucose tolerance in healthy subjects who ingest metformin compared with metformin alone

机译：与单独服用二甲双胍相比摄入圣约翰草可以改善摄入二甲双胍的健康受试者的葡萄糖耐量

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摘要

AimsOur objective was to investigate the steady-state pharmacokinetic and pharmacodynamic interaction between the antidepressive herbal medicine St John's wort and the antidiabetic drug metformin.

机译：目的我们的目的是研究抗抑郁药圣约翰草和抗糖尿病药物二甲双胍之间的稳态药代动力学和药效动力学相互作用。

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期刊名称 British Journal of Clinical Pharmacology
作者
Tore Bjerregaard Stage; Rasmus Steen Pedersen; Per Damkier; Mette Marie Hougaard Christensen; Søren Feddersen; John Teilmann Larsen; Kurt Højlund; Kim Brøsen;
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作者单位

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年(卷),期 2015(79),2
年度 2015
页码 298–306
总页数 9
原文格式 PDF
正文语种
中图分类药学;
关键词
drug–herb interaction metformin pharmacodynamics pharmacokinetics St Johns wort;

机译：药草相互作用;二甲双胍;药效动力学;药代动力学;圣约翰草;

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专利

1. Intake of St John's wort improves the glucose tolerance in healthy subjects who ingest metformin compared with metformin alone [J] . Stage Tore Bjerregaard, Pedersen Rasmus Steen, Damkier Per, British Journal of Clinical Pharmacology . 2015,第2期

机译：与单独服用二甲双胍相比，摄入圣约翰草可以改善摄入二甲双胍的健康受试者的葡萄糖耐量
2. Intake of St John's wort improves the glucose tolerance in healthy subjects who ingest metformin compared with metformin alone [J] . Stage Tore Bjerregaard, Pedersen Rasmus Steen, Damkier Per, British journal of clinical pharmacology . 2015,第2期

机译：与单独服用二甲双胍相比，摄入圣约翰草可以改善摄入二甲双胍的健康受试者的葡萄糖耐量
3. HIGH SYSTEMIC EXPOSURE OF METFORMIN WITH COMPARABLE GLUCOSE LOWERING EFFECT IN HEALTHY ELDERLY SUBJECTS COMPARED TO HEALTHY YOUNGER SUBJECTS. [J] . Jang K., Chung H., Yoon J., Clinical Pharmacology and Therapeutics . 2015,第S1期

机译：在健康老年人中，二甲双胍的高系统暴露和同等的糖代谢作用与健康的老年人相比。
4. Stability test of metformin hydrochloride in human plasma using HPLC-UV for the protocol of therapeutic drug monitoring of metformin [C] . Ari Wibowo, Vitarani D. A. Ningrum, Nailatul Izzah International Conference on Chemistry, Chemical Process and Engineering . 2018

机译：用HPLC-UV对二甲双胍治疗药物监测的HPLC-UV盐酸二甲双胍的稳定性试验
5. Metformin Pharmacogenomics: Functional Genomics of CDC25b and TPD54 Regulation of Metformin Anticancer Response in Breast Cancer [D] . Ly, Reynold. 2018

机译：二甲双胍药物基因组学：CDC25b和TPD54的功能基因组学对乳腺癌二甲双胍抗癌反应的调控
6. Addition of a Gastrointestinal Microbiome Modulator to Metformin Improves Metformin Tolerance and Fasting Glucose Levels [O] . Jeffrey H. Burton, Matthew Johnson, Jolene Johnson, 2015

机译：在二甲双胍上添加胃肠道微生物组调节剂可改善二甲双胍的耐受性和空腹血糖水平
7. Intake of St John's wort improves the glucose tolerance in healthy subjects who ingest metformin compared with metformin alone [O] . Stage, Tore Bjerregaard, Pedersen, Rasmus Steen, Damkier, Per, 2015

机译：与单独服用二甲双胍相比，摄入圣约翰草可以改善摄入二甲双胍的健康受试者的葡萄糖耐量

Intake of St Johns wort improves the glucose tolerance in healthy subjects who ingest metformin compared with metformin alone

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