A randomised clinical trial comparing 2 econazole and 5 natamycin for the treatment of fungal keratitis

机译：一项比较2％益康唑和5％那他霉素治疗真菌性角膜炎的随机临床试验

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摘要

>Aim: To compare 2% econazole and 5% natamycin in the management of fungal keratitis.>Methods: A randomised clinical trial was performed using 2% econazole or 5% natamycin as the two treatment arms on patients presenting with culture positive fungal keratitis to the cornea service at Aravind Eye Care System, Madurai, India.>Results: 116 patients were recruited, and 112 continued in the study. There were no significant differences between the two arms at baseline or for success (defined as a healed or healing ulcer) at final visit (p = 0.79).>Conclusions: 2% Econazole appears to be as effective as 5% natamycin for the management of fungal keratitis.

机译：>目标：比较2％益康唑和5％那他霉素在真菌性角膜炎治疗中的作用。>方法：使用2％益康唑或5％那他霉素作为临床试验进行了一项随机临床试验在印度马杜赖（Madurai）的Aravind眼保健系统中，对出现角膜培养阳性真菌性角膜炎的患者进行了两个治疗。两组在基线时或最终访视时成功与否（定义为已治愈的溃疡或愈合的溃疡）之间均无显着差异（p = 0.79）。>结论： 2％的益康唑与5％那他霉素用于治疗真菌性角膜炎。

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期刊名称 The British Journal of Ophthalmology
作者
N V Prajna; R K John; P K Nirmalan; P Lalitha; M Srinivasan;
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作者单位

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年(卷),期 2003(87),10
年度 2003
页码 1235–1237
总页数 3
原文格式 PDF
正文语种
中图分类眼科学;
关键词
fungal keratitis randomised clinical trial econazole natamycin;

机译：真菌性角膜炎;随机临床试验;益康唑;那他霉素;

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专利

1. A randomised clinical trial comparing 2% econazole and 5% natamycin for the treatment of fungal keratitis. [J] . Prajna NV, John RK, Nirmalan PK, British journal of ophthalmology . 2003,第10期

机译：一项比较2％益康唑和5％那他霉素治疗真菌性角膜炎的随机临床试验。
2. Re-appraisal of topical 1% voriconazole and 5% natamycin in the treatment of fungal keratitis in a randomised trial [J] . Sharma Savitri, Das Sujata, Virdi Ajoy, British journal of ophthalmology . 2015,第9期

机译：在一项随机试验中重新评估局部用1％伏立康唑和5％那他霉素治疗真菌性角膜炎
3. Concurrent use of 5% natamycin and 2% econazole for the management of fungal keratitis. [J] . Prajna NV, Nirmalan PK, Mahalakshmi R, Cornea . 2004,第8期

机译：同时使用5％游霉素和2％益康唑治疗真菌性角膜炎。
4. Non-inferiority Trial Comparing a First Generation Cephalosporin with a Third Generation Cephalosporin in the Treatment of Non-severe Clinical Mastitis in Dairy Cows [C] . Ynte h. Schukken, Mike J. Zurakowski, Brad J. Rauch, Annual Meeting of the National^Mastitis^Council . 2013

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5. Analysis of data from a clinical trial comparing different drug treatments for dyspepsia using binomial regression and binary classification trees [D] . Rose, Caren 2004

机译：使用二项式回归和二叉分类树比较一项针对消化不良的不同药物治疗的临床试验数据进行的分析
6. Topical chlorhexidine 0.2 versus topical natamycin 5 for fungal keratitis in Nepal: rationale and design of a randomised controlled non-inferiority trial [O] . Jeremy John Hoffman, Reena Yadav, Sandip Das Sanyam, 2020

机译：纯氯己定0.2％与局部野生霉素5％在尼泊尔真菌角膜炎：基本原理和设计的随机控制的非劣级审判
7. A randomised clinical trial comparing 2% econazole and 5% natamycin for the treatment of fungal keratitis [O] . Prajna, N V, John, R K, Nirmalan, P K, 2003

机译：一项比较2％益康唑和5％那他霉素治疗真菌性角膜炎的随机临床试验

A randomised clinical trial comparing 2 econazole and 5 natamycin for the treatment of fungal keratitis

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