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Identification of HLA-A2-restricted CTL epitopes of a novel tumour-associated antigen KIF20A overexpressed in pancreatic cancer

机译：胰腺癌中过表达的新型肿瘤相关抗原KIF20A的HLA-A2限制性CTL表位的鉴定

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摘要

Background: Identification of tumour-associated antigens (TAAs) that induce cytotoxic T lymphocytes (CTLs) specific to cancer cells is critical for the development of anticancer immunotherapy. In this study, we aimed at identifying a novel TAA of pancreatic cancer for immunotherapy.

机译：背景：识别诱导癌细胞特异的细胞毒性T淋巴细胞（CTL）的肿瘤相关抗原（TAA）对于开发抗癌免疫疗法至关重要。在这项研究中，我们旨在确定一种用于免疫治疗的新型胰腺癌TAA。

著录项

期刊名称 British Journal of Cancer
作者
K Imai; S Hirata; A Irie; S Senju; Y Ikuta; K Yokomine; M Harao; M Inoue; Y Tomita; T Tsunoda; H Nakagawa; Y Nakamura; H Baba; Y Nishimura;
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作者单位

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年(卷),期 2011(104),2
年度 2011
页码 300–307
总页数 8
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
anticancer immunotherapy tumour-associated antigen CTL KIF20A/RAB6KIFL/MKlp2 HLA-transgenic mouse;

机译：抗癌免疫疗法;肿瘤相关抗原;CTL;KIF20A / RAB6KIFL / MKlp2;HLA转基因小鼠;

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专利

1. Identification of HLA-A2-restricted CTL epitopes of a novel tumour-associated antigen, KIF20A, overexpressed in pancreatic cancer [J] . K Imai, S Hirata, A Irie, British Journal of Cancer . 2011,第2期

机译：鉴定新型肿瘤相关抗原，KIF20A的HLA-A2限制CTL表位，在胰腺癌中过表达
2. HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL. [J] . Harao M, Hirata S, Irie A, International Journal of Cancer =: Journal International du Cancer . 2008,第11期

机译：HLA-A2限制的新型肺癌相关癌睾丸抗原的CTL表位，与细胞分裂周期有关的1，可以诱导肿瘤反应性CTL。
3. Identification of a novel HLA-A2-restricted mutated Survivin epitope and induction of specific anti-HCC CTLs that could effectively cross-recognize wild-type Survivin antigen [J] . ShenH., ShaoH.-W., ChenX.-H., Cancer immunology, immunotherapy : . 2013,第2期

机译：鉴定新型HLA-A2限制性突变的Survivin表位并诱导可有效交叉识别野生型Survivin抗原的特异性抗HCC CTL
4. Evaluating the Antigenicity of Cancer Therapeutic Immunotoxins Using MS-Based Epitope Mapping [C] . James G. Smedley, Johanna Hansen, Masanori Onda, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：使用基于MS的表位映射来评估癌症治疗免疫毒素的抗原性
5. Identification of B-cell epitopes on domain 4 of anthrax protective antigen. [D] . Kelly-Cirino, Cassandra D. 2009

机译：鉴定炭疽保护性抗原第4结构域上的B细胞表位。
6. Identification and Enhancement of HLA-A2.1-Restricted CTL Epitopes in a New Human Cancer Antigen-POTE [O] . Yi-Hsiang Huang, Masaki Terabe, C. David Pendleton, -1

机译：新型人类癌症抗原-POTE中HLA-A2.1限制的CTL表位的鉴定和增强
7. Identification of HLA-A2-restricted CTL epitopes of a novel tumour-associated antigen, KIF20A, overexpressed in pancreatic cancer [O] . Imai, K, Hirata, S, Irie, A, 2010

机译：胰腺癌中过表达的新型肿瘤相关抗原KIF20A的HLA-A2限制性CTL表位的鉴定

Identification of HLA-A2-restricted CTL epitopes of a novel tumour-associated antigen KIF20A overexpressed in pancreatic cancer

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