MED12 TERT promoter and RBM15 mutations in primary andrecurrent phyllodes tumours

机译：初级和中级的MED12TERT启动子和RBM15突变复发性叶状肿瘤

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

Background: MED12 and TERT promoter mutations have been shown to be the most common somatic mutations in phyllodes tumours (PTs). The aims of this study were to determine the frequency of these mutations in recurrent PTs, assess whether TERT promoter mutations could be helpful in distinguishing fibroadenomas (FAs) from PTs and identify novel mutations that may be driving malignant progression.

机译：背景：MED12和TERT启动子突变已被证明是叶状肿瘤（PTs）中最常见的体细胞突变。这项研究的目的是确定复发性PT中这些突变的频率，评估TERT启动子突变是否有助于区分PT中的纤维腺瘤（FA），并鉴定可能驱动恶性进展的新突变。

著录项

期刊名称 British Journal of Cancer
作者
Diego A Garcia-Dios; Dina Levi; Vandna Shah; Cheryl Gillett; Michael A Simpson; Andrew Hanby; Ian Tomlinson; Elinor J Sawyer;
展开▼
作者单位

展开▼
年(卷),期 2018(118),2
年度 2018
页码 277–284
总页数 8
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
phyllodes tumour fibroadenoma RBM15 MED12 TERT heterogeneity;

机译：叶状肿瘤;纤维腺瘤;RBM15;MED12;TERT;异质性;

相似文献

外文文献
中文文献
专利

1. TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast [J] . Masayuki Yoshida, Reiko Ogawa, Hiroshi Yoshida, British Journal of Cancer . 2015,第8期

机译： TERT 启动子突变很常见，并且与乳腺叶状肿瘤中的 MED12 突变相关。
2. Massively parallel sequencing of phyllodes tumours of the breast reveals actionable mutations, and TERT promoter hotspot mutations and TERT gene amplification as likely drivers of progression [J] . Piscuoglio Salvatore, Ng Charlotte K. Y., Murray Melissa, Journal of Pathology: Journal of the Pathological Society of Great Britain and Ireland . 2016,第4期

机译：乳房叶状肿瘤的大规模平行测序揭示了可操作的突变，而TERT启动子热点突变和TERT基因扩增可能是进展的驱动因素
3. MED12 somatic mutations in fibroadenomas and phyllodes tumours of the breast [J] . Piscuoglio Salvatore, Murray Melissa, Fusco Nicola, Histopathology: Official Journal of the British Division of the International Academy of Pathology . 2015,第5期

机译：乳房纤维腺瘤和叶状体肿瘤中的MED12体细胞突变
4. Prediction of tumour mutational burden of squamous cell carcinoma using histopathology images of surgical specimens [C] . Salma Dammak, Matthew Cecchini, Katherina Baranova, Conference on Medical Imaging: Digital Pathology;Society of Photo-Optical Instrumentation Engineers . 2020

机译：利用手术标本的组织病理学图像预测鳞状细胞癌的肿瘤突变负担
5. Capture of colorectal circulating tumour cells for mutational analysis [D] . Nageswaran, Haritharan. 2016

机译：捕获大肠循环肿瘤细胞以进行突变分析
6. TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast [O] . Masayuki Yoshida, Reiko Ogawa, Hiroshi Yoshida, 2015

机译：TERT启动子突变很常见并且与乳房叶状肿瘤中的MED12突变相关
7. MED12, TERT promoter and RBM15 mutations in primary and recurrent phyllodes tumours [O] . Garcia-Dios, D, Levi, D, Shah, V, 2018

机译：原发性和复发性叶状肿瘤中的mED12，TERT启动子和RBm15突变

MED12 TERT promoter and RBM15 mutations in primary andrecurrent phyllodes tumours

摘要

著录项

相似文献

相关主题

期刊订阅