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Evolution of computational models in BioModels Database and the Physiome Model Repository

机译：生物模型数据库和生理组模型库中计算模型的演变

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BackgroundA useful model is one that is being (re)used. The development of a successful model does not finish with its publication. During reuse, models are being modified, i.e. expanded, corrected, and refined. Even small changes in the encoding of a model can, however, significantly affect its interpretation. Our motivation for the present study is to identify changes in models and make them transparent and traceable.

机译：背景一种有用的模型是正在（重新）使用的模型。成功模型的开发还不能以其发布结束。在重用期间，对模型进行修改，即扩展，校正和改进。但是，即使模型的编码发生很小的变化也会极大地影响其解释。我们进行本研究的动机是识别模型中的更改，并使它们透明且可追溯。

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期刊名称 BMC Systems Biology
作者
Martin Scharm; Tom Gebhardt; Vasundra Touré; Andrea Bagnacani; Ali Salehzadeh-Yazdi; Olaf Wolkenhauer; Dagmar Waltemath;
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作者单位

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年(卷),期 2018(12),-1
年度 2018
页码 53
总页数 10
原文格式 PDF
正文语种
中图分类生物学;
关键词
BioModels Physiome Model Repository Model evolution Model reuse Difference detection;

机译：生物模型;生理组模型库;模型演化;模型重用;差异检测;

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专利

1. Evolution of computational models in BioModels Database and the Physiome Model Repository [J] . Martin Scharm, Tom Gebhardt, Vasundra Touré, BMC Systems Biology . 2018,第1期

机译：生物模型数据库和生理组模型库中计算模型的演变
2. BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical and cellular systems [J] . Alexander Broicher, Benjamin Bornstein, Bruce Shapiro, Nucleic acids research . 2006,第suppla1期

机译：BioModels数据库：一个免费的集中式数据库，其中包含生化和细胞系统的精选，已发布的定量动力学模型
3. Evolution of Cardiac Biomodels from Computational to Therapeutics [J] . Rathinam Alwin Kumar, Mokhtar Raja Amin Raja The heart surgery forum . 2016,第4期

机译：心脏生物模型从计算到治疗的演变
4. A Large-Scale Assessment of Exact Model Reduction in the BioModels Repository [C] . Isabel Cristina Perez-Verona, Mirco Tribastone, Andrea Vandin International conference on computational methods in systems biology . 2019

机译：在BioModels存储库中对精确模型简化进行大规模评估
5. From gamete collection to database development: Development of a model cryopreserved germplasm repository for aquatic species with emphasis on sturgeon. [D] . Wayman, William Rittenhouse. 2003

机译：从配子的采集到数据库的开发：针对水生物种的低温保存的种质数据库的开发，重点是st鱼。
6. BioModels Database: a free centralized database of curated published quantitative kinetic models of biochemical and cellular systems [O] . Nicolas Le Novère, Benjamin Bornstein, Alexander Broicher, 2006

机译：BioModels数据库：免费的集中式数据库其中包含生化和细胞系统的精选已发布的定量动力学模型
7. BioModels Database: Next generation model repository [O] . Camille Laibe, Michael Hoehl 2010

机译：BioModels数据库：下一代模型存储库
8. Report on THMC Modeling of the Near Field Evolution of a Generic Clay Repository: Model Validation and Demonstration. [R] . Liu, H. H., Houseworth, J., Rutqvist, J., 2013

机译：关于通用粘土库近场演化的THmC建模报告：模型验证和论证。

Evolution of computational models in BioModels Database and the Physiome Model Repository

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