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Patient-rated suitability of a novel electronic device for self-injection of subcutaneous interferon beta-1a in relapsing multiple sclerosis: an international single-arm multicentre Phase IIIb study

机译：自我评估皮下干扰素β-1a注射在复发性多发性硬化中的新型电子设备的患者评价适用性：一项国际单臂多中心IIIb期研究

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BackgroundMultiple sclerosis (MS) currently requires long-term treatment with disease-modifying drugs, administered parenterally up to once daily. The need for regular self-injection can be a barrier to treatment for many patients. Autoinjectors can help patients overcome problems or concerns with self-injection and could, therefore, improve treatment adherence. This study was performed to assess the suitability of a new electronic device for the subcutaneous (sc) administration of interferon (IFN) beta-1a, 44 mcg three times weekly, for relapsing MS.

机译：背景技术多发性硬化症（MS）目前需要使用可改变病情的药物进行长期治疗，胃肠外给药每天最多一次。定期自我注射的需求可能成为许多患者治疗的障碍。自动注射器可以帮助患者克服自我注射问题或疑虑，因此可以改善治疗依从性。进行这项研究的目的是评估一种新的电子设备，对于皮下注射（sc）干扰素（IFN）β-1a，每周3次，每次44 mcg，三次。

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期刊名称 BMC Neurology
作者
Virginia Devonshire; Txomin Arbizu; Björn Borre; Michael Lang; Alessandra Lugaresi; Barry Singer; Elisabetta Verdun di Cantogno; Peter Cornelisse;
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年(卷),期 2010(10),-1
年度 2010
页码 28
总页数 12
原文格式 PDF
正文语种
中图分类神经病学;
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1. Patient-rated suitability of a novel electronic device for self-injection of subcutaneous interferon beta-1a in relapsing multiple sclerosis: an international, single-arm, multicentre, Phase IIIb study [J] . Virginia Devonshire, Txomin Arbizu, Bj?rn Borre, BMC Neurology . 2010,第1期

机译：自我评估皮下干扰素β-1a注射在复发性多发性硬化中的新型电子设备的患者评价适用性：一项国际，单臂，多中心，IIIb期研究
2. Long-term adherence of patients with relapsing-remitting multiple sclerosis to subcutaneous self-injections of interferon beta-1a using an electronic device: the RIVER study [J] . Lugaresi Alessandra, De Robertis Francesca, Clerico Marinella, Expert opinion on drug delivery . 2016,第7期

机译：RIVER研究表明，复发缓解型多发性硬化症患者长期坚持使用电子设备进行皮下自我注射干扰素β-1a
3. Patient satisfaction following transition from the original to the new formulation of subcutaneous interferon beta-1a in relapsing multiple sclerosis: a randomized, two-arm, open-label, Phase IIIb study [J] . William Camu, Karim Hadjout, Sabine Latour, Patient Preference and Adherence . 2010,第2期

机译：在复发性多发性硬化症中从皮下干扰素β-1a的原始制剂转换为新制剂后的患者满意度：一项随机，两臂，开放标签的IIIb期研究
4. Patient satisfaction following transition from the original to the new formulation of subcutaneous interferon beta-1a in relapsing multiple sclerosis: a randomized two-arm open-label Phase IIIb study [O] . William Camu, Karim Hadjout, Sabine Latour, 2010

机译：在复发性多发性硬化中从皮下注射干扰素β-1a的原始制剂转变为新制剂后的患者满意度：一项随机两臂开放标签的IIIb期研究
5. Patient-rated suitability of a novel electronic device for self-injection of subcutaneous interferon beta-1a in relapsing multiple sclerosis: an international, single-arm, multicentre, Phase IIIb study [O] . Virginia Devonshire, Txomin Arbizu, Björn Borre, 2010

机译：自我评估皮下干扰素β-1a注射在复发性多发性硬化中的新型电子设备的患者评价适用性：一项国际，单臂，多中心，IIIb期研究

Patient-rated suitability of a novel electronic device for self-injection of subcutaneous interferon beta-1a in relapsing multiple sclerosis: an international single-arm multicentre Phase IIIb study

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