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Validation of the absolute renal risk of dialysis/death in adults with IgA nephropathy secondary to Henoch-Schönlein purpura: a monocentric cohort study

机译:单核群研究验证了成年人Henoch-Schönlein紫癜继发IgA肾病的成年人透析/死亡的绝对肾脏风险:

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摘要

BackgroundWe established earlier the absolute renal risk (ARR) of dialysis/death (D/D) in primary IgA nephropathy (IgAN) which permitted accurate prospective prediction of final prognosis. This ARR was based on the potential presence at initial diagnosis of three major, independent, and equipotent risk factors such as hypertension, quantitative proteinuria ≥ 1 g per day, and severe pathological lesions appreciated by our local classification scoring ≥ 8 (range 0–20). We studied the validity of this ARR concept in secondary IgAN to predict future outcome and focused on Henoch-Schönlein purpura (HSP) nephritis.
机译:背景我们较早地确定了原发性IgA肾病(IgAN)透析/死亡(D / D)的绝对肾脏风险(ARR),从而可以对最终的预后进行准确的前瞻性预测。该ARR基于最初诊断时可能存在的三个主要,独立且均等的危险因素,例如高血压,定量蛋白尿≥≥1g /天和严重病理性病变,我们通过本地分类评分≥≥8(范围为0-20 )。我们研究了在继发性IgAN中该ARR概念的有效性,以预测未来结果,并重点研究了过敏性紫癜(HSP)肾炎。

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