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首页> 美国卫生研究院文献>BMC Medical Research Methodology >Assignment of adverse event indexing terms in randomized clinical trials involving spinal manipulative therapy: an audit of records in MEDLINE and EMBASE databases
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Assignment of adverse event indexing terms in randomized clinical trials involving spinal manipulative therapy: an audit of records in MEDLINE and EMBASE databases

机译：在涉及脊椎手法治疗的随机临床试验中分配不良事件索引项：对MEDLINE和EMBASE数据库中的记录进行审核

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BackgroundReporting of adverse events in randomized clinical trials (RCTs) is encouraged by the authors of The Consolidated Standards of Reporting Trials (CONSORT) statement. With robust methodological design and adequate reporting, RCTs have the potential to provide useful evidence on the incidence of adverse events associated with spinal manipulative therapy (SMT). During a previous investigation, it became apparent that comprehensive search strategies combining text words with indexing terms was not sufficiently sensitive for retrieving records that were known to contain reports on adverse events. The aim of this analysis was to compare the proportion of articles containing data on adverse events associated with SMT that were indexed in MEDLINE and/or EMBASE and the proportion of those that included adverse event-related words in their title or abstract.
机译：背景合并临床试验报告标准（CONSORT）声明的作者鼓励在随机临床试验（RCT）中报告不良事件。通过强有力的方法设计和适当的报告，RCT可以为脊柱操纵治疗（SMT）相关不良事件的发生率提供有用的证据。在之前的调查中，很明显，将文字与索引词结合起来的综合搜索策略对于检索已知包含不良事件报告的记录不够敏感。该分析的目的是比较在MEDLINE和/或EMBASE中索引的包含与SMT相关的不良事件数据的文章的比例，以及在标题或摘要中包含与不良事件相关的词语的文章的比例。

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