首页> 美国卫生研究院文献>BMC Medical Genomics >Association of SNPs in LCP1 and CTIF with hearing in 11 year old children: Findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort and the G-EAR consortium

【2h】

Association of SNPs in LCP1 and CTIF with hearing in 11 year old children: Findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort and the G-EAR consortium

机译：LCP1和CTIF中SNP与11岁儿童的听力的关联：雅芳父母和儿童纵向研究（ALSPAC）出生队列和G-EAR联合会的发现

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

BackgroundThe genetic basis of hearing loss in humans is relatively poorly understood. In recent years, experimental approaches including laboratory studies of early onset hearing loss in inbred mouse strains, or proteomic analyses of hair cells or hair bundles, have suggested new candidate molecules involved in hearing function. However, the relevance of these genes/gene products to hearing function in humans remains unknown. We investigated whether single nucleotide polymorphisms (SNPs) in the human orthologues of genes of interest arising from the above-mentioned studies correlate with hearing function in children.

机译：背景技术人类对听力损失的遗传基础了解甚少。近年来，包括对近交小鼠品系的早期发作性听力损失进行实验室研究或对毛细胞或发束进行蛋白质组学分析在内的实验方法已提出了涉及听力功能的新候选分子。然而，这些基因/基因产物与人类听力功能的相关性仍然未知。我们调查了由上述研究引起的人类感兴趣基因直向同源物中的单核苷酸多态性（SNP）是否与儿童的听力功能相关。

著录项

期刊名称 BMC Medical Genomics
作者
Sean Harrison; Sarah J. Lewis; Amanda J. Hall; Dragana Vuckovic; Giorgia Girotto; Richard M. Martin; Josephine C. Adams;
展开▼
作者单位

展开▼
年(卷),期 2015(8),-1
年度 2015
页码 48
总页数 13
原文格式 PDF
正文语种
中图分类遗传学;
关键词
ALSPAC Hearing Otoacoustic emission Hair cells Stereocilia Children;

机译：ALSPAC;听力;耳声发射;毛细胞;立体声病;儿童;

相似文献

外文文献
中文文献

1. Association of SNPs in LCP1 and CTIF with hearing in 11?year old children: Findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort and the G-EAR consortium [J] . Sean Harrison, Sarah J. Lewis, Amanda J. Hall, BMC Medical Genomics . 2015,第1期

机译：LCP1和CTIF中SNP与11岁儿童的听力的关联：雅芳父母和儿童纵向研究（ALSPAC）出生队列和G-EAR联合会的发现
2. The Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort as a resource for studying psychopathology in childhood and adolescence: a summary of findings for depression and psychosis [J] . Niarchou Maria, Zammit Stanley, Lewis Glyn Social psychiatry and psychiatric epidemiology . 2015,第7期

机译：雅芳父母和儿童纵向研究（ALSPAC）队列作为研究儿童和青少年心理病理学的资源：抑郁症和精神病研究结果的摘要
3. The association between autism spectrum disorder and psychotic experiences in the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort [J] . SullivanS., RaiD., GoldingJ., Journal of the American Academy of Child and Adolescent Psychiatry . 2013,第8期

机译：雅芳父母和儿童纵向研究（ALSPAC）队列中自闭症谱系障碍与精神病经历之间的关联
4. Prenatal, Early-Life and Lifetime Exposure to Air Pollution and Childhood Lung Function and Asthma: The Avon Longitudinal Study of Parents and Children (ALSPAC) Cohort Study [C] . Yutong Cai, Anna Hansell, Raquel Granell, Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：产前，生命中和生命中的空气污染与儿童肺功能和哮喘的暴露：父母和儿童的Avon纵向研究（ALSPAC）队列研究
5. The school year and parents' perceptions about themselves, their children and the educational process. A longitudinal study of the parenting experience, differentiated challenges, coping strategies and relevance of family composition on parent well-being. [D] . Osborne, Cynthia M. 2006

机译：学年和父母对自己，孩子和教育过程的看法。对育儿经历，不同挑战，应对策略以及家庭构成对父母幸福感的相关性进行纵向研究。
6. Data relating to change in locus of control orientation of parents overtime (from pre-birth to 20 years later) participating in the Avon Longitudinal Study of Parents and Children (ALSPAC) [O] . Yasmin Iles-Caven, Jean Golding, Genette Ellis, 2018

机译：参与父母（APAC）雅芳纵向研究（ALSPAC）的父母加班（从出生前到20年后）加班的控制方向发生变化的数据
7. Association of SNPs in LCP1 and CTIF with hearing in 11 year old children:findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort and the G-EAR consortium [O] . Harrison, Sean, Lewis, Sarah J., Hall, Amanda J., 2015

机译：LCP1和CTIF中SNP与11岁儿童听力的关联：雅芳父母和儿童纵向研究（ALSPAC）出生队列和G-EAR联合会的发现

Association of SNPs in LCP1 and CTIF with hearing in 11 year old children: Findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort and the G-EAR consortium

摘要

著录项

相似文献

相关主题

期刊订阅