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首页> 美国卫生研究院文献>Journal of Physical Therapy Science >Retrogression of Nervous Fibers According to the Age of Patients withDiabetes Mellitus (DM)
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Retrogression of Nervous Fibers According to the Age of Patients withDiabetes Mellitus (DM)

机译：神经纤维的退缩根据患者的年龄糖尿病（DM）

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[Purpose] This study was performed to discover the possible onset time of diabetic neuropathy by age of diabetic patients, and to provide the knowledge necessary for preventing or managing diabetic neuropathy. [Subjects] The subjects of this study were outpatients who visited D Hospital Department of Neurology with complaints of significant neuropathic symptoms including dullness, numbness and paraesthesia. [Methods] Stimulations of 5 Hz, 250 Hz and 2,000 Hz were generated with a Neurometer CPT (Neurotron Inc., Baltimore, MD, USA) and delivered selectively to C fibers, A-delta fibers and A-beta fibers. The intensity of the stimulations of 5 Hz, 250 Hz and 2,000 Hz was incrementally increased as much as 0.01 mA. [Result] The results of this experiment show that the period of retrogression of nervous fibers was different significantly according to the age of patients with diabetes mellitus. Especially, in the case of individuals in their 50's, Aβ, Aδ, and C fibers in both the right and left lower limbs significantly changed within a period of 2 months. In the case of individuals in their 60's, Aβ and C fibers of the right lower limb meaningfully changed 2 months after the onset of the disease, and Aβ, Aδ, and C fibers of the left lower limb also significantly changed within a period of 2 months. [Conclusion] We discovered that patients suffering from DM especially in their 50's or 60's should be thoroughly followed for their condition, right from the onset of DM, inorder to prevent the retrogression of nervous fibers.
机译：［目的］进行本研究以发现糖尿病患者年龄的可能程度，并为预防或管理糖尿病性神经病提供必要的知识。 [受试者]本研究的受试者为门诊，就诊于D医院神经内科，主诉有明显的神经病理症状，包括呆滞，麻木和感觉异常。 [方法]用Neurometer CPT（Neurotron Inc.，Baltimore，MD，USA）产生5 Hz，250 Hz和2,000 Hz的刺激，并选择性地递送至C纤维，A-δ纤维和A-β纤维。 5 Hz，250 Hz和2,000 Hz的刺激强度逐渐增加至0.01 mA。 [结果]本实验结果表明，神经纤维的退缩期根据糖尿病患者的年龄而有显着差异。尤其是对于50多岁的个体，右下肢和左下肢的Aβ，Aδ和C纤维在2个月内发生了显着变化。对于60多岁的个体，在疾病发作后2个月，右下肢的Aβ和C纤维发生了有意义的变化，并且在2个月内，左下肢的Aβ，Aδ和C纤维也发生了显着变化个月。 [结论]我们发现，从DM发病之日起，尤其是在50或60年代患有DM的患者，应对其病情进行彻底随访。为了防止神经纤维的倒退。

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