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Widespread hepatitis B virus genotype G (HBV-G) infection during the early years of the HIV epidemic in the Netherlands among men who have sex with men

机译:在荷兰与男性发生性行为的艾滋病毒流行的早期期间广泛传播的乙型肝炎病毒基因型G(HBV-G)感染

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摘要

BackgroundHepatitis B virus (HBV) variants belong to different genotypes, A-J, whose worldwide distribution is linked with geography, probably because viral spread was associated with ancient human migrations. HBV genotype G (HBV-G) is an aberrant genotype with little sequence divergence, suggesting a recent origin. HBV-G is strongly associated with certain risk groups such as intravenous drug users (IDUs) and men who have sex with men (MSM), but hardly with geography. The origin and epidemiology of HBV-G remain unresolved, as is the disease association.
机译:背景乙型肝炎病毒(HBV)变体属于不同的基因型A-J,其全球分布与地理位置有关,可能是因为病毒的传播与古代人类迁徙有关。 HBV基因型G(HBV-G)是异常的基因型,序列差异很小,表明其起源最近。 HBV-G与某些危险人群密切相关,例如静脉吸毒者(IDU)和与男性发生性关系的男性(MSM),但几乎与地理环境无关。 HBV-G的起源和流行病学仍未解决,疾病关联仍未解决。

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