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Histopathological characterization of corrosion product associated adverse local tissue reaction in hip implants: a study of 285 cases

机译：髋关节植入物中腐蚀产物相关的不良局部组织反应的组织病理学特征：研究285例

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BackgroundAdverse local tissue reaction (ALTR), characterized by a heterogeneous cellular inflammatory infiltrate and the presence of corrosion products in the periprosthetic soft tissues, has been recognized as a mechanism of failure in total hip replacement (THA). Different histological subtypes may have unique needs for longitudinal clinical follow-up and complication rates after revision arthroplasty. The purpose of this study was to describe the histological patterns observed in the periprosthetic tissue of failed THA in three different implant classes due to ALTR and their association with clinical features of implant failure.

机译：背景技术不良的局部组织反应（ALTR）以异质性细胞炎性浸润和假体周围软组织中腐蚀产物的存在为特征，已被认为是全髋关节置换术（THA）失败的机制。不同的组织学亚型可能对人工关节置换术后的纵向临床随访和并发症发生率有独特的需求。这项研究的目的是描述在三种不同的ALTR植入物类型的THA失败的假体周围组织中观察到的组织学模式，以及它们与植入物失败的临床特征的关系。

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期刊名称 BMC Clinical Pathology
作者
Benjamin F. Ricciardi; Allina A. Nocon; Seth A. Jerabek; Gabrielle Wilner; Elianna Kaplowitz; Steven R. Goldring; P. Edward Purdue; Giorgio Perino;
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作者单位

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年(卷),期 2016(16),-1
年度 2016
页码 3
总页数 17
原文格式 PDF
正文语种
中图分类病理学;
关键词
Adverse local tissue reaction Corrosion products Revision arthroplasty Synovial inflammation Metal-on-metal total hip replacement Hip resurfacing;

机译：不良的局部组织反应;腐蚀产物;关节置换术;滑膜炎;金属对全髋关节置换;髋关节置换;

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1. Histopathological characterization of corrosion product associated adverse local tissue reaction in hip implants: a study of 285 cases [J] . Benjamin F. Ricciardi, Allina A. Nocon, Seth A. Jerabek, BMC Clinical Pathology . 2016,第1期

机译：髋关节植入物中腐蚀产物相关的不良局部组织反应的组织病理学特征：研究285例
2. Adverse local tissue reaction (ALTR) associated with corrosion products in metal-on-metal and dual modular neck total hip replacements is associated with upregulation of interferon gamma-mediated chemokine signaling [J] . Kolatat Kritti, Perino Giorgio, Wilner Gabrielle, Journal of orthopaedic research . 2015,第10期

机译：金属对金属和双模块颈部全髋关节置换术中与腐蚀产物相关的局部组织反应不良（ALTR）与干扰素γ介导的趋化因子信号转导上调有关
3. Implant based differences in adverse local tissue reaction in failed total hip arthroplasties: a morphological and immunohistochemical study [J] . Giorgio Perino, Benjamin F Ricciardi, Seth A Jerabek, BMC Clinical Pathology . 2014,第1期

机译：全髋关节置换术失败的局部组织反应中基于植入物的差异：形态学和免疫组化研究
4. Diagnosis and Management of Adverse Local Tissue Reactions Secondary to Products of Tribocorrosion [C] . Darren R. Plummer, Craig J. Della Valle, Richard A. Berger, Symposium on modularity and tapers in total joint replacement devices . 2015

机译：诊断和管理二次诊断杂交产品
5. Practicum Three, August 2000. Novel applications of carbon-13 indirect detection NMR to metabolic tracer studies in small tissue samples. Practicum Two, December 1998. Proton and platinum-195 NMR spectroscopic characterization of the products formed in reactions of N-isobutyramide-Gly-Phe-Leu-Gly-ethylenediamine and similar model ligands with potassium tetrachloroplatinate (II). Practicum One, August 1997. Synthesis of a polyamide containing repeating macrocyclic chelate units: Evaluation of its gadolinium(3+) complex as a MRI contrast agent. [D] . Burgess, Shawn C. 2000

机译：实习三，2000年8月。Carbon-13间接检测NMR在小组织样品中代谢示踪剂研究中的新应用。实习二，1998年12月。在N-异丁酰胺-Gly-Phe-Leu-Gly-乙二胺和类似的模型配体与四氯铂酸钾（II）反应中形成的产物的质子和铂195 NMR光谱表征。实习生一，1997年8月。包含重复的大环螯合单元的聚酰胺的合成：g（3+）复合物作为MRI造影剂的评估。
6. Corrosion at the Head-Neck Taper as a Cause for Adverse Local Tissue Reactions After Total Hip Arthroplasty [O] . H. John Cooper, Craig J. Della Valle, Richard A. Berger, -1

机译：全髋关节置换术后局部组织反应不良的原因是头颈部锥度的腐蚀
7. Histopathological characterization of corrosion product associated adverse local tissue reaction in hip implants: a study of 285 cases [O] . 2016

机译：髋关节植入物中腐蚀产物相关的不良局部组织反应的组织病理学特征：研究285例
8. USE OF THE FLUORESCENT ANTIBODY METHOD IN STUDYING ANTIGEN-ANTIBODY REACTION IN TISSUES. STUDY OF LOCALIZATION OF ANTIRENAL AND ANTIHEPATIC ANTIBODIES IN HOMO-AND HETEROLOGOUS TISSUES, [R] . kolker, i. i. 1965

机译：荧光抗体法在组织抗原 - 抗体反应研究中的应用。异种和异种组织中抗原和抗肝抗体定位的研究，

Histopathological characterization of corrosion product associated adverse local tissue reaction in hip implants: a study of 285 cases

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