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Is plant mitochondrial RNA editing a source of phylogenetic incongruence? An answer from in silico and in vivo data sets

机译:植物线粒体RNA编辑是否是系统发生不一致的来源?来自计算机模拟和体内数据集的答案

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摘要

BackgroundIn plant mitochondria, the post-transcriptional RNA editing process converts C to U at a number of specific sites of the mRNA sequence and usually restores phylogenetically conserved codons and the encoded amino acid residues. Sites undergoing RNA editing evolve at a higher rate than sites not modified by the process. As a result, editing sites strongly affect the evolution of plant mitochondrial genomes, representing an important source of sequence variability and potentially informative characters.To date no clear and convincing evidence has established whether or not editing sites really affect the topology of reconstructed phylogenetic trees. For this reason, we investigated here the effect of RNA editing on the tree building process of twenty different plant mitochondrial gene sequences and by means of computer simulations.
机译:背景技术在植物线粒体中,转录后RNA编辑过程在mRNA序列的许多特定位点将C转换为U,通常可恢复系统发育上保守的密码子和编码的氨基酸残基。进行RNA编辑的位点比未经过该过程修饰的位点进化的速率更高。结果,编辑位点强烈影响植物线粒体基因组的进化,代表了序列变异性和潜在的信息特征的重要来源。迄今为止,尚无明确且令人信服的证据确定编辑位点是否真的影响重建的系统树的拓扑结构。因此,在这里我们通过计算机模拟研究了RNA编辑对二十种不同植物线粒体基因序列的构建过程的影响。

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