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首页> 美国卫生研究院文献>BMC Bioinformatics >Protected Research Information Management Environment (PRIME) provides a secure open source data management option for clinical and scientific research
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Protected Research Information Management Environment (PRIME) provides a secure open source data management option for clinical and scientific research

机译：受保护的研究信息管理环境（PRIME）为临床和科学研究提供了安全的开源数据管理选项

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The Biomedical Information Sciences Unit (BISU) of the UT-CTSI developed a secure, centralized information management system that is accessed through web applications. This system, called Slim-Prim [,], is mounted on an Oracle server housed within the UT-ITS and currently hosts three multi-site clinical trials and several institutional trials. In addition, Slim-Prim houses databases of clinical and laboratory information and provides a centralized location for several physician-generated surveys. In the majority of these cases users have approached the BISU and asked for assistance with their data management needs. Slim-Prim [,] and the BISU provide a cost effective mechanism for funded groups to handle their data management needs. However, we are also aware that many smaller groups are in desperate need of secure yet flexible database solutions; thus there is the need for a portable, secure and open source instance of Slim-Prim. To this end we have developed and released an open source instance of the Slim-Prim system under the Affero GPL v3 () called “Protected Research Information Management Environment (PRIME)”. The PRIME instance is written in PHP, based on an objected-oriented programming (OOP) architecture, and JavaScript with inverted file indexing search algorithms to render the graphical user interface (GUI) (). PRIME has a user-friendly interface that is menu driven with help features that assist the user in navigating through the application. PRIME exploits the MySQL database system and allows powerful SQL queries across tasks through using fully normalized table structures (). It is a web-enabled application that runs on most popular browsers. It is provided to the clinical and translational science community as a free and easily customized database solution.
机译：UT-CTSI的生物医学信息科学部门（BISU）开发了一个安全的集中式信息管理系统，可以通过Web应用程序对其进行访问。该系统称为Slim-Prim [，]，安装在UT-ITS内的Oracle服务器上，目前承载着三个多站点临床试验和几个机构试验。此外，Slim-Prim拥有临床和实验室信息数据库，并为多个医生生成的调查提供了集中的位置。在大多数情况下，用户已与BISU联系并要求其数据管理需求方面的帮助。 Slim-Prim [，]和BISU为受资助的团体提供了一种经济高效的机制来处理其数据管理需求。但是，我们也意识到，许多较小的团体迫切需要安全而灵活的数据库解决方案。因此，需要一种可移植，安全且开源的Slim-Prim实例。为此，我们在Affero GPL v3（）下开发并发布了Slim-Prim系统的开源实例，称为“受保护的研究信息管理环境（PRIME）”。 PRIME实例是用PHP编写的，它基于面向对象的编程（OOP）架构，以及具有反向文件索引搜索算法的JavaScript以呈现图形用户界面（GUI）（）。 PRIME具有用户友好的界面，该界面由菜单驱动，具有帮助用户在应用程序中导航的帮助功能。 PRIME利用MySQL数据库系统，并通过使用完全规范化的表结构（）跨任务执行强大的SQL查询。它是可在大多数流行的浏览器上运行的基于Web的应用程序。它是作为免费且易于定制的数据库解决方案提供给临床和转化科学界的。

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