• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>The Journal of Neuroscience >Excitotoxic Lesions of the Amygdala Fail to Produce Impairment in Visual Learning for Auditory Secondary Reinforcement But Interfere with Reinforcer Devaluation Effects in Rhesus Monkeys
【2h】

Excitotoxic Lesions of the Amygdala Fail to Produce Impairment in Visual Learning for Auditory Secondary Reinforcement But Interfere with Reinforcer Devaluation Effects in Rhesus Monkeys

机译：扁桃体的兴奋性毒性损害未能在视觉学习中产生听觉辅助强化的视觉障碍但会干扰恒河猴的强化剂贬值效应。

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Aspiration lesions of the amygdala were found previously to produce a severe impairment in visual discrimination learning for auditory secondary reinforcement in rhesus monkeys (). To determine whether excitotoxic amygdala lesions would also produce this effect, we trained four naive rhesus monkeys on the same task. The monkeys were required to learn 40 new visual discrimination problems per session in a situation in which visual choices were guided by an auditory secondary reinforcer that had been previously associated with food reward. Bilateral excitotoxic lesions of the amygdala had no effect on the rate of learning visual discrimination problems for auditory secondary reinforcement. We also tested the amygdalectomized monkeys on a reinforcer devaluation task and compared their performance with a group of three normal monkeys. The monkeys first learned to discriminate 60 pairs of objects, baited with two different food rewards. Each of the food rewards was then devalued by selective satiation in two separate experimental sessions. Normal controls tended to avoid displacing objects that covered the devalued food to a significantly greater degree than did the amygdalectomized monkeys, indicating that the excitotoxic amygdala damage interfered with reinforcer devaluation effects. Our results are consistent with the idea that the amygdala is necessary for learning the association between stimuli and the value of particular food rewards; however, the amygdala is not necessary for maintaining the value of secondary reinforcers, once they have been learned.
机译：先前已发现杏仁核的抽吸损伤在视觉辨别学习中对恒河猴的听觉次级强化产生严重损害（）。为了确定兴奋性扁桃体损伤是否也会产生这种效果，我们在同一任务上训练了四只幼稚的恒河猴。在视觉选择由先前与食物奖励相关联的听觉辅助强化指导的情况下，要求猴子每节学习40个新的视觉辨别问题。扁桃体的双侧兴奋性损害对听觉继发强化的学习视觉辨别问题的发生率没有影响。我们还测试了在增援物贬值任务下经扁桃体切除的猴子，并将它们的表现与三只正常猴子进行比较。猴子首先学会辨别60对物体，并用两种不同的食物奖励诱饵。然后，在两个单独的实验阶段中，通过选择性饱食使每种食物奖励贬值。正常对照倾向于避免覆盖被贬值食物的物体比杏仁扁桃体切除的猴子移位的程度要大得多，这表明兴奋性扁桃体损害会影响增强剂的贬值作用。我们的结果与以下观点一致：杏仁核对于学习刺激与特定食物奖励的价值之间的联系是必不可少的。但是，一旦了解到，杏仁核对于维持辅助增强剂的价值并不是必需的。

著录项

相似文献

  • 外文文献
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号