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首页> 美国卫生研究院文献>Behavioural Neurology >Assessment of Hair Aluminum Lead and Mercury in a Sample of Autistic Egyptian Children: Environmental Risk Factors of Heavy Metals in Autism
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Assessment of Hair Aluminum Lead and Mercury in a Sample of Autistic Egyptian Children: Environmental Risk Factors of Heavy Metals in Autism

机译：埃及自闭症儿童样本中头发铝铅和汞的评估：自闭症中重金属的环境危险因素

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Background and Aims. The etiological factors involved in the etiology of autism remain elusive and controversial, but both genetic and environmental factors have been implicated. The aim of this study was to assess the levels and possible environmental risk factors and sources of exposure to mercury, lead, and aluminum in children with autism spectrum disorder (ASD) as compared to their matched controls. Methods. One hundred ASD children were studied in comparison to 100 controls. All participants were subjected to clinical evaluation and measurement of mercury, lead, and aluminum through hair analysis which reflects past exposure. Results. The mean Levels of mercury, lead, and aluminum in hair of the autistic patients were significantly higher than controls. Mercury, lead, and aluminum levels were positively correlated with maternal fish consumptions, living nearby gasoline stations, and the usage of aluminum pans, respectively. Conclusion. Levels of mercury, lead, and aluminum in the hair of autistic children are higher than controls. Environmental exposure to these toxic heavy metals, at key times in development, may play a causal role in autism.
机译：背景和目标。自闭症病因中涉及的病因因素仍然难以捉摸和存在争议，但是遗传因素和环境因素都已被牵连。这项研究的目的是评估自闭症谱系障碍（ASD）儿童与其配对对照相比的水平和可能的环境危险因素以及汞，铅和铝的暴露来源。方法。与100名对照组相比，研究了100名ASD儿童。通过反映过去接触的头发分析，对所有参与者进行了汞，铅和铝的临床评估和测量。结果。自闭症患者的头发中汞，铅和铝的平均水平显着高于对照组。汞，铅和铝的含量分别与产妇的鱼类消费，附近加油站的生活以及铝盘的使用呈正相关。结论。自闭症儿童的头发中汞，铅和铝的含量高于对照组。在开发的关键时刻，暴露于这些有毒重金属的环境可能会导致自闭症。

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