Suction skin blister skin window and skin chamber techniques to determine extravascular passage of cefotaxime in humans.

机译：抽吸皮肤水泡皮肤窗口和皮肤腔室技术以测定头孢噻肟在人体内的血管外通道。

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We report the results obtained in comparative study on the extravascular passage of cefotaxime, employing three different methods: suction skin blister, skin window, and skin chamber. Applying the skin blister method in two different ways, we also studied the influence that suction pressure and time lapse between blister formation and antibiotic injection had on the results obtained in order to standardize the method and establish repeatability of the results. Using the skin chamber method, we studied the influence that the different protein contents in the fluid used to fill the skin chamber had on extravascular concentrations.

机译：我们报告使用三种不同方法对头孢噻肟的血管外通道进行比较研究的结果：抽吸皮肤水泡，皮肤窗口和皮肤腔。我们以两种不同的方式应用皮肤起泡法，我们还研究了抽吸压力和起泡与抗生素注射之间的时间间隔对获得的结果的影响，以便使该方法标准化并确定结果的可重复性。使用皮肤腔法，我们研究了用于填充皮肤腔的液体中不同蛋白质含量对血管外浓度的影响。

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期刊名称 Antimicrobial Agents and Chemotherapy
作者
R F Frongillo; L Galuppo; A Moretti;
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作者单位

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年(卷),期 1981(19),1
年度 1981
页码 22–28
总页数 7
原文格式 PDF
正文语种
中图分类药学;微生物学;
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1. Distribution to the skin of penciclovir after oral famciclovir administration in healthy volunteers: comparison of the suction blister technique and cutaneous microdialysis. [J] . Borg N, Gotharson E, Benfeldt E, Acta Dermato-Venereologica . 1999,第4期

机译：在健康志愿者中口服泛昔洛韦后，喷昔洛韦在皮肤上的分布：吸塑技术与皮肤微透析的比较。
2. Modified skin window technique for the extended characterisation of acute inflammation in humans. [J] . Marks DJ, Radulovic M, McCartney S, Inflammation research: Official journal of the European Histamine Research Society . 2007,第4期

机译：改良的皮肤窗口技术可扩展人类急性炎症的特征。
3. A suction blister model reliably assesses skin barrier restoration and immune response [J] . Smith Tracey J., Wilson Marques A., Young Andrew J., Journal of Immunological Methods . 2015,第Null期

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4. Development of test methods for determining the skin-to-core bond strength of thick-skinned sandwich constructions [C] . M R L GOWER, G D SIMS, J RATCLIFFE, Joining and repair of plastics and composites . 1999

机译：确定厚皮夹心结构的皮-芯粘结强度测试方法的开发
5. Instrument Design and Build of the Microvascular Imaging System for the Rodent Dorsal Skinfold Window Chamber and its Applications. [D] . Indrawan, Elmer Samuel. 2011

机译：啮齿动物背皮折叠窗腔室微血管成像系统的仪器设计与建造及其应用。
6. The autoimmune blistering skin disease bullous pemphigoid. The presence of plasmin/alpha 2-antiplasmin complexes in skin blister fluid indicates plasmin generation in lesional skin. [O] . M D Kramer, J Reinartz 1993

机译：自身免疫性水疱性皮肤疾病大疱性类天疱疮。皮肤水疱液中纤溶酶/α2-抗纤溶酶复合物的存在表明病变皮肤中产生了纤溶酶。
7. Suction skin blister, skin window, and skin chamber techniques to determine extravascular passage of cefotaxime in humans. [O] . Frongillo, R F, Galuppo, L, Moretti, A 1981

机译：抽吸皮肤水泡，皮肤窗口和皮肤腔室技术，以测定头孢噻肟在人体内的血管外通道。

Suction skin blister skin window and skin chamber techniques to determine extravascular passage of cefotaxime in humans.

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