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Real-Time PCR detection and quantitation of Helicobacter pylori clarithromycin-resistant strains in archival material and correlation with Sydney classification

机译：档案材料中幽门螺杆菌克拉霉素抗性菌株的实时PCR检测和定量分析及其与悉尼分类的关系

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BackgroundHelicobacter pylori (H. pylori), infects gastric mucosa causing gastritis. Treatment failure is mainly due to certain genetic changes in the peptidyltransferase loop of 23S rRNA of the microorganism. The aim of the study was to evaluate genetic changes in gastric biopsies of H. pylori (+) patients that lead to clarithromycin resistance and to correlate them with histology data.

机译：背景幽门螺杆菌（H. pylori）感染引起胃炎的胃粘膜。治疗失败主要是由于微生物的23S rRNA的肽基转移酶环发生某些遗传变化。该研究的目的是评估导致幽门螺杆菌耐药的幽门螺杆菌（+）患者胃活检的遗传变化，并将其与组织学数据相关联。

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期刊名称 Annals of Gastroenterology
作者
Sofia Gazi; Andreas Karameris; Marios Christoforou; Niki Agnantis; Theodore Rokkas; Dimitrios Stefanou;
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作者单位

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年(卷),期 2013(26),3
年度 2013
页码 226–232
总页数 7
原文格式 PDF
正文语种
中图分类肠道病毒与肝炎病毒;肝及胆疾病;肠疾病;
关键词
Clarithromycin resistance ClariRes assay real-time PCR quantitative real-time PCR histology Sydney classification Helicobacter pylori infection;

机译：克拉霉素抗性;ClariRes测定;实时荧光定量PCR;实时荧光定量PCR;组织学;悉尼分类;幽门螺杆菌感染;

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专利

1. Detection of Clarithromycin-Resistant Helicobacter pylori by Stool PCR in Children: A Comprehensive Review of Literature [J] . Lijing Xiong, Yu Tong, Zhiling Wang, Helicobacter . 2013,第2期

机译：凳PCR检测儿童抗克拉霉素的幽门螺杆菌：文献综述
2. Efficacy of real-time PCR-based detection of Helicobacter pylori infection and genotypic resistance-guided quadruple therapy as the first-line treatment for functional dyspepsia with Helicobacter pylori infection [J] . Liu Qian, Qi Dongdong, Kang Jiarui, European journal of gastroenterology and hepatology . 2015,第3期

机译：基于实时PCR的幽门螺杆菌感染检测和基因型耐药指导的四联疗法作为功能性消化不良合并幽门螺杆菌的一线治疗的功效
3. Comparative efficacy of 23 SrRNA gene mutation examination and microbial culture sensitivity test for detection of clarithromycin-resistant Helicobacter pylori strains [J] . Noriyuki H., Okuse H., Miura H., Helicobacter . 2017,第S1期

机译：23 srRNA基因突变检测和微生物培养敏感性试验检测克拉霉素抗幽门螺杆菌菌株的比较疗效
4. Interlaboratory Validation of a qPCR Method to Detect Helicobacter pylori in Drinking Water [C] . Yildiz Chambers, Keya Sen, Misty L. Pope, AWWA water quality technology conference exposition . 2009

机译：qPCR方法检测饮用水中幽门螺杆菌的实验室间验证
5. Detection of Escherichia coli ATCCRTM 8739(TM) and Aspergillus brasiliensis ATCCRTM16404(TM) in Raw Materials and Pharmaceutical Products Using the Real-Time PCR in Comparison with Standard Conventional Microbiological Methods. [D] . Garcia, Elsie Jacqueline Hernandez. 2016

机译：与标准常规微生物学方法相比，使用实时PCR检测原料药和药品中的大肠杆菌ATCCRTM 8739™和巴西曲霉ATCCRTM16404™。
6. Detection of Clarithromycin-Resistant Helicobacter pylori Strains by a Preferential Homoduplex Formation Assay [O] . Shin Maeda, Haruhiko Yoshida, Hironari Matsunaga, 2000

机译：首选同源双链体形成法检测耐克拉霉素的幽门螺杆菌菌株
7. Lipopolysaccharide structures of Helicobacter pylori genomic strains 26695 and J99, mouse model H. pylori Sydney strain, H. pylori P466 carrying sialyl Lewis X, and H. pylori UA915 expressing Lewis B [O] . Monteiro, M. A., Appelmelk, B. J., Rasko, D. A., 2000

机译：幽门螺杆菌基因组菌株26695和J99，小鼠模型幽门螺杆菌悉尼菌株，携带唾液酸路易斯Lewis X的幽门螺杆菌P466和表达路易斯B的幽门螺杆菌UA915的脂多糖结构

Real-Time PCR detection and quantitation of Helicobacter pylori clarithromycin-resistant strains in archival material and correlation with Sydney classification

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