首页> 美国卫生研究院文献>AMIA Annual Symposium Proceedings >IV. Clinical Consultation Systems Medical Decision Support Systems and Clinical Research Data Bases: A. Medical Decision Support and Artificial Intelligence Methodologies: RECONSIDER: A Program for Generating Differential Diagnoses
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IV. Clinical Consultation Systems Medical Decision Support Systems and Clinical Research Data Bases: A. Medical Decision Support and Artificial Intelligence Methodologies: RECONSIDER: A Program for Generating Differential Diagnoses

机译:IV。临床咨询系统医疗决策支持系统和临床研究数据库:A.医疗决策支持和人工智能方法:反思:生成差异诊断的程序

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摘要

RECONSIDER is an interactive computer program which produces a differential diagnosis given a list of patient attributes. The program's principal knowledge base is a corpus of 3,262 disease definitions represented in the form of structured natural language text. As these definitions were originally prepared for human use, RECONSIDER uses medical knowledge that is semantically identical to an information source that might be used by a physician. Thus, RECONSIDER can explain the inclusion of a particular disease in a differential by displaying the way in which the disease's definition relates to the list of patient attributes, and by ranking the strength of this relation relative to the rest of the differential.Use of RECONSIDER is illustrated on cases from the literature, and a case of pyruvate kinase deficiency (PK disease). Included for comparison are cases diagnosed by INTERNIST[1] and PIP[2], two well known diagnosis programs.
机译:RECONSIDER是一种交互式计算机程序,可根据给定的患者属性列表进行鉴别诊断。该计划的主要知识库是一个3,262种疾病定义的语料库,以结构化自然语言文本的形式表示。由于这些定义最初是供人使用的,因此RECONSIDER使用的医学知识在语义上与医师可能使用的信息源相同。因此,RECONSIDER可以通过显示疾病定义与患者属性列表相关的方式,并通过相对于其他差异的相关性等级进行排序,来解释特定疾病是否包含在差异中。在文献中的病例和丙酮酸激酶缺乏症(PK疾病)的病例中都有说明。为了比较,其中包括由两个著名的诊断程序INTERNIST [1]和PIP [2]诊断的病例。

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