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首页> 美国卫生研究院文献>African Journal of Traditional Complementary and Alternative Medicines >Effects of Gan Lian Yu Ping Feng Powder on the Antibody Titers to Infectious Laryngotracheitis Vaccine and Some Nonspecific Immune Indexes in Chickens
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Effects of Gan Lian Yu Ping Feng Powder on the Antibody Titers to Infectious Laryngotracheitis Vaccine and Some Nonspecific Immune Indexes in Chickens

机译：肝莲玉平风散对鸡传染性喉气管炎疫苗抗体滴度和某些非特异性免疫指标的影响

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The study was conducted in order to investigate the immuno-enhancing property of the Chinese herbal formula, Gan lian Yu ping feng powder. Three hundred and thirty six 45-day-old chicks were randomly divided into eight groups. The chicks in groups >A, B, C were orally given 0.25 g/mL (low-), 0.5 g/mL (middle-) and 1.0 g/mL (high) dose of Gan lian Yu ping feng powder in the drinking water respectively for 3 days consecutively. They were then immunised with infectious laryngotracheitis vaccine (ILTV) on the 4th day. Groups >D, E, F were given 0.25 g/mL, 0.5 g/mL and 1.0 g/mL dose of Gan lian Yu ping feng powder respectively after the immunisation for three days consecutively. Group >G was Wen du qing (a government approved herbal product for ILT) control group, and group >H was blank control group. At 52, 59, 73, 87 days of age, 8 chicks of each group were selected randomly for blood sampling to determine the levels of IFN-γ, IL-4 and the antibody of ILT. Then the chickens were sacrificed, with the thymus, spleen and Bursa of Fabricius being weighed for the calculation of immune organ indexes. The results showed that high and middle dosages of Gan lian Yu ping feng powder given at the day before immunisation and 3 days after immunisation elevated not only the contents of IFN-γ, the antibody titers of ILT (P<0.01) and the immune organ indexes (P<0.05) significantly, but also reduced the contents of IL-4. There was a significantly different degree of enhancement in the content of IFN-γ, the antibody of ILT (P<0.01) and the immune organ index (P<0.05). The results indicate that Gan lian Yu ping feng powder effectively improves the immunity in chickens.
机译：进行这项研究是为了研究中草药配方甘莲鱼平风粉的免疫增强特性。将336只45天大的小鸡随机分为八组。分别给> A，B，C 组的小鸡口服0.25 g / mL（低剂量），0.5 g / mL（中剂量）和1.0 g / mL（高剂量）的甘连鱼坪枫粉分别在饮用水中连续3天。然后在第4天用传染性喉气管炎疫苗（ILTV）对其进行免疫。免疫三天后，分别给> D，E，F 组分别服用0.25 g / mL，0.5 g / mL和1.0 g / mL剂量的甘莲鱼平风粉。 > G 组是温杜清（政府批准用于ILT的草药产品）对照组，而> H 组是空白对照组。在第52、59、73、87日龄时，随机选择每组8只小鸡进行血液采样，以确定IFN-γ，IL-4和ILT抗体的水平。然后将鸡处死，称取胸腺，脾脏和Fabricius的伯氏囊称重以计算免疫器官指数。结果表明，在免疫前一日和免疫后3天给予高剂量和中剂量的甘连鱼平风粉不仅提高了IFN-γ的含量，而且提高了ILT的抗体滴度（P <0.01）和免疫器官。指标（P <0.05）显着，但也降低了IL-4的含量。 IFN-γ含量，ILT抗体（P <0.01）和免疫器官指数（P <0.05）的提高程度有显着差异。结果表明，甘莲鱼平风粉可有效提高鸡的免疫力。

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