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首页> 美国卫生研究院文献>Advanced Pharmaceutical Bulletin >Antimicrobial and Cytotoxic Activity of Three Bitter Plants Enhydra Fluctuans Andrographis Peniculata and Clerodendrum Viscosum.
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Antimicrobial and Cytotoxic Activity of Three Bitter Plants Enhydra Fluctuans Andrographis Peniculata and Clerodendrum Viscosum.

机译：三种苦味植物Enhydra Flutters穿心莲和粘菌纤维的抗菌和细胞毒性活性。

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>Purpose: In this study, three important medicinal plants (Enhydra fluctuans Lour, Clerodendrum viscosum Vent and Andrographis peniculata Wall) of Bangladesh were investigated to analyze their antimicrobial and cytotoxic activities against some pathogenic microorganisms and Artemia salina (brine shrimp nauplii). >Methods: The coarse powder material of leaves of each plant was extracted separately with methanol and acetone to yield methanol extracts of leaves of Enhydra fluctuans (MLE), Clerodendrum viscosum (MLC) and Andrographis peniculata (MLA), and acetone extracts of leaves of Enhydra fluctuans (ALE), Clerodendrum viscosum (ALC) and Andrographis peniculata (ALA). The disc diffusion method and the method described by Meyer were used to determine the antimicrobial and cytotoxic activities of each plant extract. >Results: Among the test samples, MLE and ALE showed comparatively better antimicrobial activity against a number of bacteria and fungi with inhibition zones in the range of 06-15 mm and according to the intensity of activity, the efficacy against microorganisms were found in the order of Enhydra fluctuans > Andrographis peniculata > Clerodendrum viscosum. In cytotoxicity assay, all samples were found to be active against brine shrimp nauplii (Artemia salina) and ALA produced lowest LC50 value (7.03 μg/ml). >Conclusion: Enhydra fluctuans and Andrographis peniculata possesses significant antimicrobial and cytotoxic activities.
机译：>目的：在本研究中，研究了孟加拉国的三种重要药用植物（Enhydra fluctuans Lour，Vlersum Viscosum Vent和Andrographis peniculata Wall），以分析其对某些病原微生物和盐卤（盐卤）的抗微生物和细胞毒性活性。虾无节幼体）。 >方法：用甲醇和丙酮分别提取每株植物叶片的粗粉，得到Enhydra fluctuans（MLE），Clerodendrum viscosum（MLC）和Andrographis peniculata（MLA）的甲醇提取物，的水和波动的叶片（ALE），粘菌毛（ALC）和穿心莲（ALA）的丙酮和丙酮提取物。圆盘扩散法和Meyer描述的方法用于确定每种植物提取物的抗微生物和细胞毒性活性。 >结果：在测试样品中，MLE和ALE对多种细菌和真菌表现出相对较好的抗菌活性，其抑制区在06-15 mm范围内，并且根据活性强度，其功效对微生物的抗性依次为：Enhydra fluctuans> Andrographis peniculata> Clerodendrum viscosum。在细胞毒性测定中，发现所有样品均具有抗盐水虾无节幼体（卤虫）的活性，ALA产生最低的LC50值（7.03μg/ ml）。 >结论： Enhydra波动且穿心莲具有明显的抗菌和细胞毒活性。

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