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Associations between Job Strain and Arterial Stiffness: A Large Survey among Enterprise Employees from Thailand

机译:工作压力与动脉僵硬度之间的关联:来自泰国企业员工的一项大规模调查

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摘要

As an intermediate endpoint to cardiovascular disease, arterial stiffness has received much attention recently. So far, the research on work stress and arterial stiffness is still sparse and inconsistent, and no investigations on work stress and cardiovascular health among the Thai working population have been reported. Therefore, we conducted an epidemiological study among 2141 Thai enterprise employees (858 men and 1283 women) who were free from any diagnosed cardiovascular disease. Work stress was measured using Karasek’s Job Demand–Control model for job strain (a combination of high demand and low control). Arterial stiffness was evaluated by a non-invasive approach using pulse-wave analysis based on a finger photoplethysmogram. Multivariable linear regression was applied to examine associations between job strain and arterial stiffness. In men, job strain was significantly associated with arterial stiffness (β  =  0.078, 95% confidence interval  =  0.026 to 0.130), after accounting for sociodemographic, behavioral, dietary and biomedical factors. However, the association in women was not significant. As the first study in Thailand on work stress and cardiovascular risk, we found that job strain might be an important risk factor for cardiovascular disease among Thai working men. Further studies with longitudinal design are warranted.
机译:作为心血管疾病的中间终点,动脉僵硬度最近受到了广泛关注。迄今为止,关于工作压力和动脉僵硬度的研究仍然很少且不一致,并且尚未有关于泰国劳动人口中有关工作压力和心血管健康的调查的报道。因此,我们对2141名泰国企业员工(男性858名和女性1283名女性)进行了一次流行病学研究,他们没有被诊断出患有心血管疾病。使用Karasek的工作压力-工作压力模型(高需求和低控制的结合)来测量工作压力。通过基于手指光体积描记图的脉冲波分析,通过非侵入性方法评估动脉僵硬度。应用多元线性回归分析工作压力与动脉僵硬度之间的关系。在考虑社会人口统计学,行为,饮食和生物医学因素后,男性的工作压力与动脉僵硬度显着相关(β= 0.078,95%置信区间= 0.026至0.130)。但是,妇女的关联并不明显。作为泰国在工作压力和心血管风险方面的第一项研究,我们发现工作压力可能是泰国劳动男性中心血管疾病的重要危险因素。有必要对纵向设计进行进一步研究。

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