• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>American Journal of Epidemiology >Early Cannabis Use and Estimated Risk of Later Onset of Depression Spells: Epidemiologic Evidence From the Population-based World Health Organization World Mental Health Survey Initiative
【2h】

Early Cannabis Use and Estimated Risk of Later Onset of Depression Spells: Epidemiologic Evidence From the Population-based World Health Organization World Mental Health Survey Initiative

机译：早期使用大麻和后期抑郁症发作的估计风险：基于人口的世界卫生组织世界心理健康调查倡议的流行病学证据

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Early-onset cannabis use is widespread in many countries and might cause later onset of depression. Sound epidemiologic data across countries are missing. The authors estimated the suspected causal association that links early-onset (age <17 years) cannabis use with later-onset (age ≥17 years) risk of a depression spell, using data on 85,088 subjects from 17 countries participating in the population-based World Health Organization World Mental Health Survey Initiative (2001–2005). In all surveys, multistage household probability samples were evaluated with a fully structured diagnostic interview for assessment of psychiatric conditions. The association between early-onset cannabis use and later risk of a depression spell was studied using conditional logistic regression with local area matching of cases and controls, controlling for sex, age, tobacco use, and other mental health problems. The overall association was modest (controlled for sex and age, risk ratio = 1.5, 95% confidence interval: 1.4, 1.7), was statistically robust in 5 countries, and showed no sex difference. The association did not change appreciably with statistical adjustment for mental health problems, except for childhood conduct problems, which reduced the association to nonsignificance. This study did not allow differentiation of levels of cannabis use; this issue deserves consideration in future research.
机译：早发性大麻的使用在许多国家都很普遍，可能导致较晚的抑郁症发作。各国缺乏可靠的流行病学数据。作者使用来自参与人口调查的17个国家/地区的85,088名受试者的数据，估计了可疑的因果关系，将其与早发（年龄小于17岁）的大麻使用与晚发（年龄≥17岁）的抑郁症风险联系在一起。世界卫生组织《世界心理健康调查倡议》（2001-2005年）。在所有调查中，均采用结构完整的诊断访谈对多阶段家庭概率样本进行评估，以评估精神病状况。使用条件逻辑回归与病例和对照的局部匹配，控制性别，年龄，吸烟和其他精神健康问题，研究了早期使用大麻和以后患抑郁症风险之间的关联。总体关联度不高（控制性别和年龄，风险比= 1.5，95％置信区间：1.4、1.7），在5个国家/地区具有统计学上的优势，并且没有性别差异。除了儿童行为方面的问题外，对于心理健康问题的统计学调整，该关联没有显着变化，这将关联降低为无意义。这项研究不允许区分大麻的使用水平。这个问题值得在未来的研究中加以考虑。

著录项

相似文献

  • 外文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号