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首页> 美国卫生研究院文献>Journal of International Oral Health : JIOH >Sialochemical Analysis: Windfall to the OralPhysician (A Hospital-based Clinical Cross-Sectional Study inDepressive Disorders)
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Sialochemical Analysis: Windfall to the OralPhysician (A Hospital-based Clinical Cross-Sectional Study inDepressive Disorders)

机译：唾液化学分析：意外之财医师（医院基于临床的跨学科研究抑郁症）

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>Background: Depressive disorders, worldwide, may rank second by the year 2020. In India; about 10 million people suffer from depressive disorders, the prevalence rate being recorded as 31.2 for every 1000 individuals. A significant impairment of all personal hygiene may occur due a depressive episode which in turn may result in altered biochemical composition of some important salivary parameters. The present study was conducted in Bhopal, the heart of Madhya Pradesh, India. It was done to assess the relationship and bring about a comparison of certain selective sialochemical alterations between normal and subjects with depressive disorders. >Materials and Methods: The research participants signed a free and informed consent form authorizing their voluntary participation in the research. A total number of 150 subjects were selected and were distributed equally between 3 groups - Group I (normal), Group II (subjects withdepressive disorders who were only on psychiatric counseling) andGroup III (subjects with depressive disorders who were onmedication for at least 1 month). The effect of threeantidepressant drugs, which were commonly prescribed by thepsychiatrists were considered for the study. Stimulated wholesaliva was analyzed biochemically for α-amylase, calcium, sodium,potassium, total proteins, and urea.>Results:Stimulated salivary calcium and total protein levels were found tobe statistically significant among all three groups (P < 0.0001).Salivary amylase levels between Groups II and III and betweenGroups I and III (P < 0.0001) was statistically significant whilethe salivary urea levels between Groups I and II and betweenGroups I and III were found to be statistically significant(P < 0.0001). However, there was no statistical difference in theirsodium and potassium levels.>Conclusions:It was observed that drugs do affect the salivary composition. Itwas observed that cyclic antidepressants produced significantalteration in the sialochemical constituents of saliva as comparedto tricyclic antidepressants and tetracyclic antidepressants.>How to cite the article:Milton BA, Bhambal A, Nair P. Sialochemical analysis: Windfall tothe oral physician (A hospital-based clinical cross-sectional studyin depressive disorders). J Int Oral Health 2014;6(3):82-9.
机译：>背景：到2020年，全世界的抑郁症可能排名第二。约有1000万人患有抑郁症，患病率每1000人中记录为31.2。抑郁发作可能会严重损害所有个人卫生，进而导致某些重要唾液参数的生化成分发生变化。本研究是在印度中央邦的博帕尔进行的。进行了评估这种关系并比较了正常人和抑郁症患者之间某些选择性唾液化学变化的比较。 >材料和方法：研究参与者签署了一份免费且知情的同意书，授权他们自愿参加研究。总共选择了150名受试者，并将其平均分配给3组-I组（正常），II组（仅接受心理咨询的抑郁症患者）和第三组（患有抑郁症的受试者服药至少1个月）。效果三抗抑郁药，通常由研究考虑了精神科医生。整体刺激生化分析唾液中的α-淀粉酶，钙，钠，钾，总蛋白和尿素。>结果：发现刺激唾液钙和总蛋白水平在所有三组中具有统计学意义（P <0.0001）。组II和组III之间以及组之间的唾液淀粉酶水平I组和III组（P <0.0001）具有统计学意义，而第一组和第二组之间以及之间的唾液尿素水平发现第一和第三组具有统计学意义（P <0.0001）。但是，他们的钠和钾水平。>结论：据观察，药物确实会影响唾液成分。它观察到环状抗抑郁药产生了显着比较唾液唾液化学成分的变化三环抗抑郁药和四环抗抑郁药。>如何引用该文章：Milton BA，Bhambal A，Nair P.唾液化学分析：意外之财口腔医师（基于医院的临床横断面研究在抑郁症中）。国际口腔卫生杂志2014; 6（3）：82-9。

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