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首页> 美国卫生研究院文献>Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America >Workgroup Report by the Joint Task Force Involving American Academy of Allergy Asthma Immunology (AAAAI); Food Allergy Anaphylaxis Dermatology and Drug Allergy (FADDA) (Adverse Reactions to Foods Committee and Adverse Reactions to Drugs Biologicals and Latex Committee); and the Centers for Disease Control and Prevention Botulism Clinical Treatment Guidelines Workgroup—Allergic Reactions to Botulinum Antitoxin: A Systematic Review
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Workgroup Report by the Joint Task Force Involving American Academy of Allergy Asthma Immunology (AAAAI); Food Allergy Anaphylaxis Dermatology and Drug Allergy (FADDA) (Adverse Reactions to Foods Committee and Adverse Reactions to Drugs Biologicals and Latex Committee); and the Centers for Disease Control and Prevention Botulism Clinical Treatment Guidelines Workgroup—Allergic Reactions to Botulinum Antitoxin: A Systematic Review

机译：涉及美国过敏哮喘和免疫学学会（AAAAI）的联合工作组的工作组报告；食品过敏过敏反应皮肤病学和药物过敏（FADDA）（食品委员会的不良反应和药物生物制品和乳胶委员会的不良反应）；和疾病预防控制中心肉毒杆菌中毒临床治疗指南工作组-对肉毒杆菌毒素的过敏反应：系统评价

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BackgroundNaturally occurring botulism is rare, but a large number of cases could result from unintentional or intentional contamination of a commercial food. Despeciated, equine-derived, heptavalent botulinum antitoxin (HBAT) is licensed in the United States. Timely treatment reduces morbidity and mortality, but concerns that botulinum antitoxin can induce anaphylaxis exist. We sought to quantify the allergy risk of botulinum antitoxin treatment and the usefulness of skin testing to assess this risk.
机译：背景技术自然发生的肉毒杆菌中毒很少见，但大量情况可能是由于无意或有意污染商业食品而引起的。特定于马的七价肉毒杆菌抗毒素（HBAT）在美国获得许可。及时治疗可降低发病率和死亡率，但人们担心肉毒杆菌抗毒素会引起过敏反应。我们试图量化肉毒杆菌抗毒素治疗的过敏风险，并进行皮肤测试以评估这种风险。

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