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How Representative Are Research Tissue Biobanks of the Local Populations? Experience of the Infectious Diseases Biobank at Kings College London UK

机译:本地人群的研究组织生物库的代表性如何?英国伦敦国王学院传染病生物库的经验

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摘要

Biobanks have a primary responsibility to collect tissues that are a true reflection of their local population and thereby promote translational research, which is applicable to the community. The Infectious Diseases BioBank (IDB) at King's College London is located in the southeast of the city, an area that is ethnically diverse. Transplantation programs have frequently reported a low rate of donation among some ethnic minorities. To determine whether patients who volunteered peripheral venous blood samples to the IDB were representative of the local community, we compared local government demographic data to characteristics of patients who have donated to the IDB. There was a good match between these statistics, indicating that the IDB's volunteer population of human immunodeficiency virus patients was similar to local demographics.
机译:生物库的主要责任是收集能真实反映其当地人口的组织,从而促进适用于社区的转化研究。伦敦国王学院的传染病生物库(IDB)位于城市的东南部,该地区种族多样。移植计划经常报告一些少数民族的捐赠率很低。为了确定向IDB自愿提供外周静脉血样本的患者是否代表了当地社区,我们将当地政府的人口统计学数据与向IDB捐赠的患者的特征进行了比较。这些统计数据之间有很好的匹配,表明IDB的人类免疫缺陷病毒患者的自愿人群与当地人口统计数据相似。

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