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Towards subsidized malaria rapid diagnostic tests. Lessons learned from programmes to subsidise artemisinin-based combination therapies in the private sector: a review

机译:迈向补贴疟疾快速诊断测试。从计划中获得的经验教训以对私营部门中以青蒿素为基础的联合疗法进行补贴:回顾

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摘要

The idea of a private sector subsidy programme of artemisinin-based combination therapies (ACTs) was first proposed in 2004. Since then, several countries around the world have hosted pilot projects or programmes on subsidized ACTs and/or the Affordable Medicines Facility-malaria programme (AMFm). Overall the private sector subsidy programmes of ACTs have been effective in increasing availability of ACTs in the private sector and driving down average prices but struggled to crowd out antimalarial monotherapies. The results obtained from this ambitious strategy should inform policy makers in the designing of future interventions aimed to control malaria morbidity and mortality. Among the interventions recently proposed, a subsidy of rapid diagnostic tests (RDTs) in the private sector has been recommended by governments and international donors to cope with over-treatment with ACTs and to delay the emergence of resistance to artemisinin. In order to improve the cost-effectiveness of co-paid RDTs, we should build on the lessons we learned from almost 10 years of private sector subsidy programmes of ACTs in malaria-endemic countries.
机译:2004年首次提出了基于青蒿素的联合疗法的私营部门补贴计划的构想。此后,世界上多个国家主办了有关补贴的ACT的试点项目或计划和/或经济适用药物设施-疟疾计划。 (AMFm)。总体而言,ACT的私营部门补贴计划有效地提高了ACT在私营部门中的可获得性并压低了平均价格,但仍在努力排除抗疟药的单一疗法。从这一雄心勃勃的战略中获得的结果应为决策者设计旨在控制疟疾发病率和死亡率的未来干预措施提供信息。在最近提出的干预措施中,政府和国际捐助者已建议对私营部门的快速诊断测试(RDT)进行补贴,以应对ACT的过度治疗并延缓对青蒿素的耐药性的出现。为了提高共付RDT的成本效益,我们应该借鉴从疟疾流行国家近10年的ACT私营部门补贴计划中获得的经验教训。

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