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首页> 美国卫生研究院文献>Experimental and Therapeutic Medicine >The application of conventional us and transthoracic ultrasound elastography in evaluating peripheral pulmonary lesions
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The application of conventional us and transthoracic ultrasound elastography in evaluating peripheral pulmonary lesions

机译：常规超声和经胸超声弹性成像在评估周围性肺部病变中的应用

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The aim of the present study was to evaluate the diagnostic value of ultrasound (US) elastography in differentiating between benign and malignant peripheral lung lesions (PLLs). This retrospective study included 91 consecutive patients with 91 PLLs. Conventional US, strain elastography (SE), acoustic radiation force impulse imaging (ARFIimaging) and point share wave elastography (p-SWE) were performed. All of the pathological results were confirmed by US-guided biopsies or surgeries. There were 36 benign PLLs and 55 malignant PLLs on pathology. For conventional US, a lesion diameter ≥5 cm, irregular contour, presence of air bronchogram and non-abundant vascularity were predictive factors of malignancy (P<0.05). SE scores were observed to be invalid in differentiating between malignant and benign PLLs (P=0.542). For ARFIimaging scores, an elasticity score of 3 or greater was predictive of malignancy, with a sensitivity of 83.6% (46/55) and a specificity of 52.8% (19/36). For p-SWE, the share wave velocity of malignant PLLs was higher than benign ones (2.47±0.92 vs. 1.85±0.92 m/sec; P=0.0022). When 1.951 m/sec was selected as the cut-off value, a sensitivity of 70.9% (39/55) and a specificity of 69.4% (25/36) were obtained. Thus, US, particularly US elastography, is helpful in distinguishing malignant PLLs from benign PLLs.
机译：本研究的目的是评估超声弹性成像在鉴别良性和恶性周围性肺部病变（PLL）方面的诊断价值。这项回顾性研究纳入了91位PLL连续的91位患者。常规进行US，应变弹性成像（SE），声辐射力脉冲成像（ARFIimaging）和点共享波弹性成像（p-SWE）。所有病理结果均由美国指导的活检或手术证实。病理上有36个良性PLL和55个恶性PLL。对于常规的US，病变直径≥5cm，轮廓不规则，气管支气管造影检查存在和血管充盈是恶性肿瘤的预测因素（P <0.05）。观察到SE评分在区分恶性和良性PLL方面无效（P = 0.542）。对于ARFIimaging评分，弹性评分为3或更高可预测恶性，敏感性为83.6％（46/55），特异性为52.8％（19/36）。对于p-SWE，恶性PLL的共享波速高于良性PLL（2.47±0.92 vs. 1.85±0.92 m / sec； P = 0.0022）。当选择1.951 m / sec作为截止值时，灵敏度为70.9％（39/55），特异性为69.4％（25/36）。因此，US（尤其是US弹性成像）有助于区分恶性PLL和良性PLL。

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