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首页> 美国卫生研究院文献>Experimental and Therapeutic Medicine >Diffusion-weighted whole-body imaging with background body signal suppression/T2 image fusion for the diagnosis of colorectal polyp and cancer
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Diffusion-weighted whole-body imaging with background body signal suppression/T2 image fusion for the diagnosis of colorectal polyp and cancer

机译：扩散加权全身成像与背景体信号抑制/ T2图像融合在大肠息肉和癌症的诊断中的应用

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Diffusion-weighted whole-body imaging with background body signal suppression/T2 image fusion (DWIBS/T2) is useful for the diagnosis of cancer as it presents a clear contrast between cancerous and non-cancerous tissue. The present study investigated the limitations and advantages of DWIBS/T2 with regards to the diagnosis of colorectal polyp (CP) or cancer (CRC). The current study included patients diagnosed with CP or CRC following colonoscopy, who were subjected to DWIBS/T2 between July 2012 and March 2015. Patient records were analyzed retrospectively. Patients were subjected to DWIBS/T2 when they presented with abdominal cancers or inflammation. Colonoscopy was performed as part of screening, or if patients had suspected colon cancer or inflammatory bowel disease. A total of 8 male and 7 female patients were enrolled in the present study. All patients, with the exception of one who had been diagnosed with CRC following colonoscopy, had positive results and all patients diagnosed with CP following a colonoscopy, with the exception of one, had negative results on DWIBS/T2. Thus, CRC was detected by DWIBS/T2, while CP was not (P=0.0028). The diameter of CRC lesions was significantly larger than that of CP (P<0.0001) and that of lesions positive on DWIBS/T2 was significantly larger than that of negative lesions (P=0.0004). The depth of invasion tended to be greater for lesions positive on DWIBS/T2 compared with that of negative ones. This indicated that DWIBS/T2 may be suitable for the detection of CRC but not for detection of CP. The results of DWIBS/T2 may also be affected by lesion diameter and depth of invasion.
机译：具有背景身体信号抑制/ T2图像融合（DWIBS / T2）的扩散加权全身成像可用于癌症的诊断，因为它在癌性组织与非癌性组织之间表现出明显的对比。本研究调查了DWIBS / T2在结直肠息肉（CP）或癌症（CRC）诊断方面的局限性和优势。本研究包括2012年7月至2015年3月之间接受DWIBS / T2治疗的结肠镜检查后诊断为CP或CRC的患者。对患者记录进行回顾性分析。当患者出现腹部癌或发炎时接受DWIBS / T2治疗。结肠镜检查是筛查的一部分，如果患者怀疑患有结肠癌或炎症性肠病。本研究共招募了8位男性和7位女性患者。除一名在结肠镜检查后被诊断为CRC的患者外，所有患者均呈阳性结果，所有在结肠镜检查后被诊断为CP的患者（一例除外）DWIBS / T2阴性。因此，DWIBS / T2检测到CRC，而CP未检测到（P = 0.0028）。 CRC病变的直径明显大于CP的直径（P <0.0001），DWIBS / T2阳性的病变的直径明显大于阴性的病变（P = 0.0004）。 DWIBS / T2阳性病变的浸润深度倾向于大于阴性病变。这表明DWIBS / T2可能适用于CRC的检测，但不适用于CP的检测。 DWIBS / T2的结果也可能受到病变直径和浸润深度的影响。

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