首页> 美国卫生研究院文献>The Journal of Infectious Diseases >Surveillance of HIV Hepatitis B Virus and Hepatitis C Virus in an Estonian Injection Drug–Using Population: Sensitivity and Specificity of Testing Syringes for Public Health Surveillance
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Surveillance of HIV Hepatitis B Virus and Hepatitis C Virus in an Estonian Injection Drug–Using Population: Sensitivity and Specificity of Testing Syringes for Public Health Surveillance

机译:爱沙尼亚注射吸毒人群中HIV乙肝和丙肝病毒的监测:对公共卫生监测用注射器的敏感性和特异性

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摘要

Surveillance of bloodborne infections among injection drug users (IDUs) can be accomplished by determining the presence of pathogen markers in used syringes. Parallel testing of returned syringes and venous blood from IDUs was conducted to detect antibodies to human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). Syringe surveillance for HIV yielded a sensitivity and specificity of 92% and 89%, respectively, and provided a reasonable estimate of the prevalence of HIV among participants. Because sensitivity for HBV (34%) and HCV (55%) was low, syringe testing may be useful for surveillance of hepatitis over time but not for estimation of prevalence.
机译:可以通过确定二手注射器中病原体标记物的存在来完成对注射吸毒者(IDU)中血源性感染的监视。对返回的注射器和来自注射吸毒者的静脉血进行了并行测试,以检测针对人类免疫缺陷病毒(HIV),乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)的抗体。对艾滋病毒的注射器监测分别产生了92%和89%的敏感性和特异性,并提供了对参与者中HIV患病率的合理估计。由于对HBV(34%)和HCV(55%)的敏感性较低,因此注射器测试可能有助于长期监测肝炎,但不能用于估计患病率。

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