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首页> 美国卫生研究院文献>Medical Physics >Dependency of image quality on system configuration parameters in a stationary digital breast tomosynthesis system
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Dependency of image quality on system configuration parameters in a stationary digital breast tomosynthesis system

机译：图像质量对固定式数字乳房断层合成系统中系统配置参数的依赖性

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>Purpose: In principle, a stationary digital breast tomosynthesis (s-DBT) system has better image quality when compared to continuous motion DBT systems due to zero motion blur of the source. The authors have developed a s-DBT system by using a linear carbon nanotube x-ray source array. The purpose of the current study was to quantitatively evaluate the performance of the s-DBT system; and investigate the dependence of imaging quality on the system configuration parameters.>Methods: Physical phantoms were used to assess the image quality of each configuration including inplane resolution as measured by the modulation transfer function (MTF), inplane contrast as measured by the signal difference to noise ratio (SdNR), and depth resolution as measured by the z-axis artifact spread function. Five parameters were varied to create five groups of configurations: (1) total angular span; (2) total number of projection images; (3) distribution of exposure (mAs) across the projection images; (4) entrance dose; (5) detector pixel size.>Results: It was found that the z-axis depth resolution increased with the total angular span but was insensitive to the number of projection images, mAs distribution, entrance dose, and detector pixel size. The SdNR was not affected by the angular span or the number of projection images. A decrease in SdNR was observed when the mAs was not evenly distributed across the projection images. As expected, the SdNR increased with entrance dose and when larger pixel sizes were used. For a given detector pixel size, the inplane resolution was found to be insensitive to the total angular span, number of projection images, mAs distribution, and entrance dose. A 25% increase in the MTF was observed when the detector was operating in full resolution mode (70 μm pixel size) compared to 2 × 2 binned mode (140 μm pixel size).>Conclusions: The results suggest that the optimal imaging configuration for a s-DBT system is a large angular span, an intermittent number of projection views, and a uniform mAs distribution over all views. With the detector operating at full resolution, a stationary DBT system can achieve an inplane resolution of 5.1 cycles per mm, which is significantly better than continuous motion DBT systems.
机译：>目的：原则上，由于源的零运动模糊，固定数字乳腺断层合成（s-DBT）系统与连续运动DBT系统相比具有更好的图像质量。作者通过使用线性碳纳米管x射线源阵列开发了s-DBT系统。本研究的目的是定量评估s-DBT系统的性能。并研究成像质量对系统配置参数的依赖性。>方法：使用物理模型评估每种配置的图像质量，包括通过调制传递函数（MTF）测量的面内分辨率，面内对比度通过信号差噪比（SdNR）进行测量，以及通过z轴伪影扩展函数进行测量的深度分辨率。改变五个参数以创建五组配置：（1）总角度跨度； （2）投影图像总数； （3）投影图像上的曝光量（mAs）分布； （4）入药剂量； （5）检测器像素大小。>结果：发现z轴深度分辨率随总角度跨度增加，但对投影图像的数量，mAs分布，入射剂量和检测器不敏感像素大小。 SdNR不受角度跨度或投影图像数量的影响。当mAs不在投影图像上均匀分布时，观察到SdNR降低。不出所料，当使用更大的像素尺寸时，SdNR随入射剂量而增加。对于给定的探测器像素大小，发现平面分辨率对总角度跨度，投影图像数，mAs分布和入射剂量不敏感。当检测器在全分辨率模式（70μm像素大小）下运行时，与2×2合并模式（140μm像素大小）相比，MTF增加了25％。>结论：结果表明s-DBT系统的最佳成像配置是较大的角度跨度，间歇的投影视图数量以及在所有视图上均一的mAs分布。探测器以全分辨率运行时，固定式DBT系统可以实现每毫米5.1个周期的面内分辨率，这比连续运动DBT系统要好得多。

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