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A method for correlating in vivo prostate magnetic resonance imaging and histopathology using individualized magnetic resonance -based molds

机译:一种基于个体磁共振的模具将体内前列腺磁共振成像与组织病理学相关的方法

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摘要

A method for the design and rapid manufacture of a patient specific tissue slicing device based on in vivo images in order to facilitate the process of correlating the images with histopathology is presented. The method is applied to radical prostatectomy specimens where the customized mold is designed using magnetic resonance (MR) images of each patient obtained prior to surgery. In this case, the mold holds the prostate in place while a knife with a single blade or multiple blades is inserted in slots which are positioned to obtain tissue blocks corresponding to the slices in the MR images. The resulting histological specimens demonstrate good anatomical correlation with the MR images.
机译:提出了一种基于体内图像来设计和快速制造患者专用组织切片装置的方法,以促进将图像与组织病理学相关联的过程。该方法适用于根治性前列腺切除术标本,其中使用手术前获得的每个患者的磁共振(MR)图像设计定制模具。在这种情况下,当将具有单个刀片或多个刀片的刀插入狭槽中时,模具将前列腺保持在适当的位置,这些狭槽被定位以获得与MR图像中的切片相对应的组织块。所得的组织学标本显示出与MR图像良好的解剖相关性。

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