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首页> 美国卫生研究院文献>Medical Physics >Accelerating protons to therapeutic energies with ultraintense ultraclean and ultrashort laser pulses
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Accelerating protons to therapeutic energies with ultraintense ultraclean and ultrashort laser pulses

机译：通过超强超净和超短激光脉冲将质子加速至治疗能量

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Proton acceleration by high-intensity laser pulses from ultrathin foils for hadron therapy is discussed. With the improvement of the laser intensity contrast ratio to 10−11 achieved on the Hercules laser at the University of Michigan, it became possible to attain laser-solid interactions at intensities up to 1022 W∕cm2 that allows an efficient regime of laser-driven ion acceleration from submicron foils. Particle-in-cell (PIC) computer simulations of proton acceleration in the directed Coulomb explosion regime from ultrathin double-layer (heavy ions∕light ions) foils of different thicknesses were performed under the anticipated experimental conditions for the Hercules laser with pulse energies from 3 to 15 J, pulse duration of 30 fs at full width half maximum (FWHM), focused to a spot size of 0.8 μm (FWHM). In this regime heavy ions expand predominantly in the direction of laser pulse propagation enhancing the longitudinal charge separation electric field that accelerates light ions. The dependence of the maximum proton energy on the foil thickness has been found and the laser pulse characteristics have been matched with the thickness of the target to ensure the most efficient acceleration. Moreover, the proton spectrum demonstrates a peaked structure at high energies, which is required for radiation therapy. Two-dimensional PIC simulations show that a 150–500 TW laser pulse is able to accelerate protons up to 100–220 MeV energies.
机译：讨论了用于强子治疗的超薄箔片的高强度激光脉冲对质子的加速作用。随着密歇根大学的Hercules激光器将激光强度对比度提高到10 −11 ，在高达10 22 <的强度下实现激光-固体相互作用成为可能。 / sup> W ∕ cm 2 可以有效地实现亚微米箔片的激光驱动离子加速。在Hercules激光器的预期实验条件下，利用脉冲能量来自于不同厚度的超薄双层（重离子，轻离子）箔的定向库仑爆炸条件下的质子加速，进行了质点计算机模拟（PIC） 3至15 J，在半峰全宽（FWHM）处的脉冲持续时间为30 fs，聚焦到0.8μm的光斑大小（FWHM）。在这种情况下，重离子主要在激光脉冲传播的方向上扩展，从而增强了纵向电荷分离电场，该电场使光离子加速。已经发现最大质子能量对箔厚度的依赖性，并且激光脉冲特性已经与靶材的厚度匹配以确保最有效的加速。此外，质子谱显示出高能峰结构，这是放射治疗所必需的。二维PIC仿真显示，150-500 TW的激光脉冲能够将质子加速到100-220 MeV的能量。

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