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首页> 美国卫生研究院文献>Scientific Reports >Assessing trends of breast cancer and carcinoma in situ to monitor screening policies in developing settings
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Assessing trends of breast cancer and carcinoma in situ to monitor screening policies in developing settings

机译：评估乳腺癌和原位癌的发展趋势以监测发展中国家的筛查政策

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There have been arguments about the role of breast cancer screening at the population level, and some points of controversy have arisen, such the establishment of organized screening policies and the age at which to begin screening. The real benefit of screening has been questioned because the results of this practice may increase the diagnosis of indolent lesions without decreasing mortality due to breast cancer. The authors have proposed a study of incidence and mortality trends for breast cancer in a developing setting in Brazil to monitor the effectiveness of the official recommendations that prioritize the age group from 50 to 69 years. The database of the Cancer Registry and the Mortality Information System was used to calculate age-standardized and age-specific rates, which were then used to calculate incidence and mortality trends using the Joinpoint Regression Program. The results showed stability in trends across all ages and age-specific groups in both incidence and mortality. In conclusion, we found that incidence and mortality rates are compatible with those in regions with similar human development indexes, and trends have demonstrated stabilization. Thus, we do not endorse changes in the official recommendations to conduct screening for ages other than 50 to 69 years, nor should policy makers implement organized screening strategies.
机译：关于乳腺癌筛查在人群水平上的作用一直存在争议，并引起了一些争议，例如建立有组织的筛查政策和开始筛查的年龄。筛查的真正好处受到质疑，因为这种做法的结果可能会增加对惰性病变的诊断，而不会降低由于乳腺癌引起的死亡率。作者提出了一项研究，以研究巴西发展中的乳腺癌发病率和死亡率趋势，以监测官方建议的有效性，该建议将年龄组从50岁提高到69岁。癌症登记处和死亡率信息系统的数据库用于计算标准化年龄和特定年龄的比率，然后使用Joinpoint回归程序来计算发病率和死亡率趋势。结果显示，所有年龄段和特定年龄组的发病率和死亡率趋势均稳定。总而言之，我们发现发病率和死亡率与人类发展指标相近的地区的发病率和死亡率相符，而且趋势已经证明是稳定的。因此，我们不赞成改变对50至69岁年龄段人群进行筛查的官方建议，决策者也不应实施有组织的筛查策略。

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