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Multidisciplinary management of clear-cell renal cell carcinoma in Africa and the Middle East: current practice and recommendations for improvement

机译:非洲和中东透明细胞肾细胞癌的多学科管理:当前实践和改进建议

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摘要

The management of renal cell carcinoma (RCC) has evolved considerably in recent years. This report represents the consensus of 22 relevant medical specialists from Africa and the Middle East region engaged in the management of RCC. Partial or radical nephrectomy is the standard of care for most patients with localized RCC. It is essential that patients are followed up appropriately after surgery to enable local and distant relapses to be identified and treated promptly. The treatment of advanced/metastatic disease has changed dramatically with the introduction of targeted therapies. Follow-up of these patients enables therapy optimization and assessment of response to treatment. There was universal agreement on the importance of management of RCC by a multidisciplinary team supported by a multidisciplinary tumor board. Barriers hindering this approach were identified. These included lack of awareness of the benefits of multidisciplinary team role, poor communication among relevant disciplines, time constraints, and specifics of private practice. Other challenges include shortage of expert specialists as urologists and oncologists and lack of local management guidelines in some countries. Solutions were proposed and discussed. Medical educational initiatives and awareness activities were highlighted as keys to encouraging cooperation between specialties to improve patients’ outcome. Establishing combined genitourinary cancer clinics and formal referral systems should encourage a culture of effective communication. Joining forces with professionals in peripheral areas and the private sector is likely to help standardize care. Sustained action will be required to ensure that all patients with RCC in the region benefit from up-to-date care.
机译:近年来,肾细胞癌(RCC)的管理已取得了长足发展。该报告代表了来自非洲和中东地区从事RCC管理的22位相关医学专家的共识。部分或根治性肾切除术是大多数局部RCC患者的治疗标准。术后必须对患者进行适当的随访,以使局部和远处复发得以迅速识别和治疗,这一点至关重要。随着靶向治疗的引入,晚期/转移性疾病的治疗发生了巨大变化。这些患者的随访能够优化治疗方案并评估对治疗的反应。由多学科肿瘤委员会支持的多学科团队对RCC的管理重要性达成了普遍共识。确定了阻碍这种方法的障碍。其中包括缺乏对多学科团队角色的好处的认识,相关学科之间的沟通不畅,时间限制以及私人执业的具体情况。其他挑战包括缺少泌尿科和肿瘤科专家,以及一些国家缺乏当地管理指南。提出并讨论了解决方案。医学教育计划和意识活动被强调为鼓励各专业之间合作以改善患者预后的关键。建立泌尿生殖系统癌症综合诊所和正式的转诊系统应鼓励有效沟通的文化。与周边地区和私营部门的专业人士联手可能有助于规范护理。将需要采取持续措施,以确保该地区所有RCC患者都能从最新护理中受益。

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