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首页> 美国卫生研究院文献>Oncology Letters >Fast-track laparoscopic surgery: A better option for treating colorectal cancer than conventional laparoscopic surgery
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Fast-track laparoscopic surgery: A better option for treating colorectal cancer than conventional laparoscopic surgery

机译：快速腹腔镜手术：比常规腹腔镜手术更好的治疗结直肠癌的选择

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Fast-track surgery (FTS), a multimodal rehabilitation technique, has been recommended as surgical therapy for colorectal cancer. The objective of the present study was to compare the outcomes of FTS and conventional laparoscopic surgery. This study was a blinded randomized trial. A total of 70 patients with colorectal cancer were divided into two groups and underwent laparoscopic colorectal resection. The FTS group consisted of 31 patients and the control group consisted of 39 patients. Protocols for the treatment of the FTS group included skipping pre-operative mechanical bowel preparation, early restoration of diet and early post-operative ambulation. Outcome measures, length of hospital stay, post-operative surgical stress response [C-reactive protein (CRP)] and post-operative complications were compared between the two groups. The average length of total hospital stay for the FTS and the control groups was 5.9±0.8 and 10.9±1.3 days, respectively (P<0.05), and the length of post-operative hospital stay for the FTS and control group was 4.3±0.8 and 8.0±1.1 days, respectively. (P<0.05) First flatus time for the FTS and control groups was 1.6±0.8 and 2.5±0.9 days, respectively (P<0.05). Defecation time for the FTS and control groups was 2.2±0.7 and 4.5±0.7 days, respectively (P<0.05). The time to restoration of a solid diet also showed a significant difference between the FTS and control groups (1.1±0.3 vs. 3.6±0.9 days; P<0.05). Following surgery, due to post-operative surgical stress, the two groups CRP levels increased significantly, but the levels of the FTS group were lower than those of the conventional control group (P<0.05). There was no difference in post-operative complications between the FTS and control groups. This study confirms that FTS shortens hospital stay and accelerates the recovery of bowel function without increase of post-operative complications. FTS is safe, improves post-operative recovery and is a better option than conventional laparoscopic surgery for treating colorectal cancer patients.
机译：已建议将快速通道外科手术（FTS）作为一种多模式康复技术，作为结直肠癌的外科治疗方法。本研究的目的是比较FTS和常规腹腔镜手术的结果。这项研究是一项随机双盲试验。将总共​​70例结直肠癌患者分为两组，并进行腹腔镜大肠切除术。 FTS组由31例患者组成，对照组由39例组成。 FTS组的治疗方案包括跳过术前机械性肠准备，早期恢复饮食和术后早期活动。比较两组的结果指标，住院时间，术后手术应激反应[C反应蛋白（CRP）]和术后并发症。 FTS和对照组的平均总住院时间分别为5.9±0.8天和10.9±1.3天（P <0.05），FTS和对照组的术后总住院时间为4.3±0.8和8.0±1.1天。 （P <0.05）FTS组和对照组的首次肠胃气胀时间分别为1.6±0.8天和2.5±0.9天（P <0.05）。 FTS和对照组的排便时间分别为2.2±0.7天和4.5±0.7天（P <0.05）。恢复固态饮食的时间在FTS和对照组之间也显示出显着差异（1.1±0.3天与3.6±0.9天； P <0.05）。手术后，由于术后压力，两组的CRP水平明显升高，但FTS组的水平低于常规对照组（P <0.05）。 FTS组和对照组之间的术后并发症没有差异。这项研究证实，FTS可以缩短住院时间并加速肠功能的恢复，而不会增加术后并发症。与传统的腹腔镜手术相比，FTS安全，可提高术后恢复率，是治疗结直肠癌患者的更好选择。

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