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Hepatectomy for spontaneous rupture of hepatocellular carcinoma without portal triad clamping

机译:肝切除术自发性肝细胞癌破裂而无需三叉门夹

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摘要

Hepatectomy without portal triad clamping may decrease the incidence of liver injury; however, the effects of hepatectomy without portal triad clamping in the treatment of spontaneous rupture of hepatocellular carcinoma (SRHCC) remain unclear. The aims of the present study were to evaluate the therapeutic value of hepatectomy without portal triad clamping in the treatment of patients with SRHCC. The present study retrospectively reviewed patients with SRHCC who received hepatectomy without portal triad clamping (non-clamping group) and the therapeutic efficacy was compared with that of 20 patients with SRHCC undergoing the same surgery in the presence of portal triad clamping (clamping group). Following hepatectomy, the non-clamping group exhibited a significantly lower incidence of acute liver failure compared with the clamping group (P<0.05). No significant differences in operative time, intra-operative blood loss, disease-free or overall survival times between the two groups were identified (all P>0.05). At 1 week and 2 weeks after surgery, the non-clamping group exhibited significantly lower alanine aminotransferase, aspartate aminotransferase and total bilirubin serum levels compared with the clamping group (all P<0.05). Hepatectomy without portal triad clamping may decrease the incidence of liver injury and liver failure in patients with SRHCC, suggesting that it may be a safe and effective therapeutic strategy.
机译:肝切除术不钳夹三联征可降低肝损伤的发生率;然而,没有门诊三叉神经钳夹术的肝切除术在自发性肝细胞癌破裂(SRHCC)治疗中的作用尚不清楚。本研究的目的是评估无门诊三联症钳夹的肝切除术在SRHCC患者中的治疗价值。本研究回顾性回顾了未进行门静脉三联症钳夹的肝切除术的SRHCC患者(非钳夹组),并将其与20例在门静脉三联征钳夹下进行相同手术的SRHCC患者的疗效进行了比较(钳夹组)。肝切除术后,非固定组的急性肝功能衰竭发生率比固定组低(P <0.05)。两组的手术时间,术中失血量,无病生存时间或总生存时间均无显着差异(均P> 0.05)。术后1周和2周,非钳制组与钳制组相比,丙氨酸转氨酶,天冬氨酸转氨酶和总胆红素水平明显降低(均P <0.05)。没有门诊三联症钳夹的肝切除术可以降低SRHCC患者的肝损伤和肝衰竭的发生率,这表明这可能是一种安全有效的治疗策略。

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